{ "resourceType" : "Bundle", "id" : "748683741", "meta" : { "profile" : ["https://fhir.nwgenomics.nhs.uk/StructureDefinition/BundleMessage"] }, "language" : "en", "identifier" : { "value" : "748683741" }, "type" : "message", "timestamp" : "2025-11-11T07:47:53+00:00", "entry" : [{ "fullUrl" : "urn:uuid:f2ae3b74-9199-4ca3-972c-d3de93c7e65c", "resource" : { "resourceType" : "MessageHeader", "language" : "en", "text" : { "status" : "generated", "div" : "

Generated Narrative: MessageHeader

event: event: O21 (OML - Laboratory order)

Destinations

-EndpointReceiver
*https//fhir.nwgenomics.nhs.uk/Endpoint/iGeneIdentifier: ODS Organisation Code/SMHGEN

sender: Identifier: ODS Organisation Code/MFT

Sources

-SoftwareEndpoint
*NW GLHhttps://fhir.north-west.england.nhs.uk/Endpoint/EpicBeaker

focus:

" }, "eventCoding" : { "system" : "http://terminology.hl7.org/CodeSystem/v2-0003", "code" : "O21" }, "destination" : [{ "endpoint" : "https//fhir.nwgenomics.nhs.uk/Endpoint/iGene", "receiver" : { "identifier" : { "system" : "https://fhir.nhs.uk/Id/ods-organization-code", "value" : "SMHGEN" } } }], "sender" : { "identifier" : { "system" : "https://fhir.nhs.uk/Id/ods-organization-code", "value" : "MFT" } }, "source" : { "software" : "NW GLH", "endpoint" : "https://fhir.north-west.england.nhs.uk/Endpoint/EpicBeaker" }, "focus" : [{ "reference" : "urn:uuid:fbbf3f64-4fee-44de-ac11-da98a32ff1b4" }, { "reference" : "urn:uuid:af7d8130-2940-4743-beb3-1d904c14e3aa" }, { "reference" : "urn:uuid:f6f3ba92-549f-42e8-80ec-b91251048d21" }] } }, { "fullUrl" : "urn:uuid:2cc74315-590b-463e-a999-ef58d0255f5c", "resource" : { "resourceType" : "Patient", "language" : "en", "text" : { "status" : "generated", "div" : "

Generated Narrative: Patient

Lori Johnson Female, DoB: 2013-10-21 ( Medical record number)

Contact Detail1979 MILKY WAY "" VERONA 53593
" }, "identifier" : [{ "type" : { "coding" : [{ "system" : "http://terminology.hl7.org/CodeSystem/v2-0203", "code" : "MR" }] }, "system" : "https://nw-gmsa.github.io/Id/MR", "value" : "207003", "assigner" : { "identifier" : { "system" : "https://fhir.nhs.uk/Id/ods-organization-code", "value" : "R0A" } } }], "name" : [{ "family" : "Johnson", "given" : ["Lori"], "prefix" : ["\"\""] }], "gender" : "female", "birthDate" : "2013-10-21", "address" : [{ "line" : ["1979 MILKY WAY", "\"\""], "city" : "VERONA", "district" : "WI", "postalCode" : "53593" }] } }, { "fullUrl" : "urn:uuid:1b9d42c1-ef8e-445a-a8d8-2a8a48aa1404", "resource" : { "resourceType" : "PractitionerRole", "language" : "en", "text" : { "status" : "generated", "div" : "

Generated Narrative: PractitionerRole

practitioner: ARMITAGE, GEMMA (Identifier: GMC Number/999)

organization: MANCHESTER UNIVERSITY NHS FOUNDATION TRUST (Identifier: ODS Organisation Code/R0A)

" }, "practitioner" : { "identifier" : { "system" : "https://fhir.hl7.org.uk/Id/gmc-number", "value" : "999" }, "display" : "ARMITAGE, GEMMA" }, "organization" : { "identifier" : { "system" : "https://fhir.nhs.uk/Id/ods-organization-code", "value" : "R0A" }, "display" : "MANCHESTER UNIVERSITY NHS FOUNDATION TRUST" } } }, { "fullUrl" : "urn:uuid:9355d363-cc63-4bcb-a57f-6ef82dd0e6c3", "resource" : { "resourceType" : "Observation", "language" : "en", "text" : { "status" : "generated", "div" : "

Generated Narrative: Observation

identifier: https://fhir.nwgenomics.nhs.uk/Id/ResourceIdentifier/R0A-1000162341-230056-IGENE

status: Final

code: What Type of Referral Do You Require?

subject: Lori Johnson Female, DoB: 2013-10-21 ( Medical record number)

effective: 2025-11-11 07:47:48+0000

value: Standard

" }, "identifier" : [{ "system" : "https://fhir.nwgenomics.nhs.uk/Id/ResourceIdentifier", "value" : "R0A-1000162341-230056-IGENE", "assigner" : { "identifier" : { "system" : "https://fhir.nhs.uk/Id/ods-organization-code", "value" : "R0A" } } }], "status" : "final", "code" : { "coding" : [{ "system" : "https://fhir.nwgenomics.nhs.uk/CodeSystem/MFTQuestionIds", "code" : "230056", "display" : "What Type of Referral Do You Require?" }] }, "subject" : { "reference" : "urn:uuid:2cc74315-590b-463e-a999-ef58d0255f5c" }, "effectiveDateTime" : "2025-11-11T07:47:48+00:00", "valueString" : "Standard" } }, { "fullUrl" : "urn:uuid:d2955ceb-4d4b-4ef7-9808-d4ad401036b7", "resource" : { "resourceType" : "Observation", "language" : "en", "text" : { "status" : "generated", "div" : "

Generated Narrative: Observation

identifier: https://fhir.nwgenomics.nhs.uk/Id/ResourceIdentifier/R0A-1000162341-230048-IGENE

status: Final

code: Please Select Clinical Indication(s)

subject: Lori Johnson Female, DoB: 2013-10-21 ( Medical record number)

effective: 2025-11-11 07:47:48+0000

value: M213: Glial and Glioneuronal Tumour Differential - Paediatric

" }, "identifier" : [{ "system" : "https://fhir.nwgenomics.nhs.uk/Id/ResourceIdentifier", "value" : "R0A-1000162341-230048-IGENE", "assigner" : { "identifier" : { "system" : "https://fhir.nhs.uk/Id/ods-organization-code", "value" : "R0A" } } }], "status" : "final", "code" : { "coding" : [{ "system" : "https://fhir.nwgenomics.nhs.uk/CodeSystem/MFTQuestionIds", "code" : "230048", "display" : "Please Select Clinical Indication(s)" }] }, "subject" : { "reference" : "urn:uuid:2cc74315-590b-463e-a999-ef58d0255f5c" }, "effectiveDateTime" : "2025-11-11T07:47:48+00:00", "valueString" : "M213: Glial and Glioneuronal Tumour Differential - Paediatric" } }, { "fullUrl" : "urn:uuid:42a459ac-1540-434a-a65f-fe1d9dbc9c9f", "resource" : { "resourceType" : "Observation", "language" : "en", "text" : { "status" : "generated", "div" : "

Generated Narrative: Observation

identifier: https://fhir.nwgenomics.nhs.uk/Id/ResourceIdentifier/R0A-1000162341-231610-IGENE

status: Final

code: Clinical Utility (Please Select as Appropriate and Provide Any Additional Information in the Comments Section)

subject: Lori Johnson Female, DoB: 2013-10-21 ( Medical record number)

effective: 2025-11-11 07:47:48+0000

value: Patient management (determining therapeutic decisions and/or clinical investigations and/or surveillance programme)

" }, "identifier" : [{ "system" : "https://fhir.nwgenomics.nhs.uk/Id/ResourceIdentifier", "value" : "R0A-1000162341-231610-IGENE", "assigner" : { "identifier" : { "system" : "https://fhir.nhs.uk/Id/ods-organization-code", "value" : "R0A" } } }], "status" : "final", "code" : { "coding" : [{ "system" : "https://fhir.nwgenomics.nhs.uk/CodeSystem/MFTQuestionIds", "code" : "231610", "display" : "Clinical Utility (Please Select as Appropriate and Provide Any Additional Information in the Comments Section)" }] }, "subject" : { "reference" : "urn:uuid:2cc74315-590b-463e-a999-ef58d0255f5c" }, "effectiveDateTime" : "2025-11-11T07:47:48+00:00", "valueString" : "Patient management (determining therapeutic decisions and/or clinical investigations and/or surveillance programme)" } }, { "fullUrl" : "urn:uuid:819110cc-da75-4428-a674-ca94328c45eb", "resource" : { "resourceType" : "Observation", "language" : "en", "text" : { "status" : "generated", "div" : "

Generated Narrative: Observation

identifier: https://fhir.nwgenomics.nhs.uk/Id/ResourceIdentifier/R0A-1000162341-230030-IGENE

status: Final

code: Neoplastic Cell Content Level

subject: Lori Johnson Female, DoB: 2013-10-21 ( Medical record number)

effective: 2025-11-11 07:47:48+0000

value: <10%

" }, "identifier" : [{ "system" : "https://fhir.nwgenomics.nhs.uk/Id/ResourceIdentifier", "value" : "R0A-1000162341-230030-IGENE", "assigner" : { "identifier" : { "system" : "https://fhir.nhs.uk/Id/ods-organization-code", "value" : "R0A" } } }], "status" : "final", "code" : { "coding" : [{ "system" : "https://fhir.nwgenomics.nhs.uk/CodeSystem/MFTQuestionIds", "code" : "230030", "display" : "Neoplastic Cell Content Level" }] }, "subject" : { "reference" : "urn:uuid:2cc74315-590b-463e-a999-ef58d0255f5c" }, "effectiveDateTime" : "2025-11-11T07:47:48+00:00", "valueString" : "<10%" } }, { "fullUrl" : "urn:uuid:fc9bd807-fd99-49db-903c-2577b2e92b3e", "resource" : { "resourceType" : "Observation", "language" : "en", "text" : { "status" : "generated", "div" : "

Generated Narrative: Observation

identifier: https://fhir.nwgenomics.nhs.uk/Id/ResourceIdentifier/R0A-1000162341-230038-IGENE

status: Final

code: Please Confirm the Pathology Report will Accompany the Sample to the Laboratory

subject: Lori Johnson Female, DoB: 2013-10-21 ( Medical record number)

effective: 2025-11-11 07:47:48+0000

value: Yes

" }, "identifier" : [{ "system" : "https://fhir.nwgenomics.nhs.uk/Id/ResourceIdentifier", "value" : "R0A-1000162341-230038-IGENE", "assigner" : { "identifier" : { "system" : "https://fhir.nhs.uk/Id/ods-organization-code", "value" : "R0A" } } }], "status" : "final", "code" : { "coding" : [{ "system" : "https://fhir.nwgenomics.nhs.uk/CodeSystem/MFTQuestionIds", "code" : "230038", "display" : "Please Confirm the Pathology Report will Accompany the Sample to the Laboratory" }] }, "subject" : { "reference" : "urn:uuid:2cc74315-590b-463e-a999-ef58d0255f5c" }, "effectiveDateTime" : "2025-11-11T07:47:48+00:00", "valueString" : "Yes" } }, { "fullUrl" : "urn:uuid:2336e28c-3bff-4220-82d9-7843dd6d981c", "resource" : { "resourceType" : "Observation", "language" : "en", "text" : { "status" : "generated", "div" : "

Generated Narrative: Observation

identifier: https://fhir.nwgenomics.nhs.uk/Id/ResourceIdentifier/R0A-1000162341-230027-IGENE

status: Final

code: Email Addresses of Non-MFT Clinicians for Result Reports

subject: Lori Johnson Female, DoB: 2013-10-21 ( Medical record number)

effective: 2025-11-11 07:47:48+0000

value: peter.volek@mft.nhs.uk

" }, "identifier" : [{ "system" : "https://fhir.nwgenomics.nhs.uk/Id/ResourceIdentifier", "value" : "R0A-1000162341-230027-IGENE", "assigner" : { "identifier" : { "system" : "https://fhir.nhs.uk/Id/ods-organization-code", "value" : "R0A" } } }], "status" : "final", "code" : { "coding" : [{ "system" : "https://fhir.nwgenomics.nhs.uk/CodeSystem/MFTQuestionIds", "code" : "230027", "display" : "Email Addresses of Non-MFT Clinicians for Result Reports" }] }, "subject" : { "reference" : "urn:uuid:2cc74315-590b-463e-a999-ef58d0255f5c" }, "effectiveDateTime" : "2025-11-11T07:47:48+00:00", "valueString" : "peter.volek@mft.nhs.uk" } }, { "fullUrl" : "urn:uuid:01a0493d-b41d-4d5d-9223-fac8358a15fa", "resource" : { "resourceType" : "Observation", "language" : "en", "text" : { "status" : "generated", "div" : "

Generated Narrative: Observation

identifier: https://fhir.nwgenomics.nhs.uk/Id/ResourceIdentifier/R0A-1000162341-230029-IGENE

status: Final

code: Confirmation of Consent for Testing - MANDATORY Testing will not be performed without completed confirmation of consent

subject: Lori Johnson Female, DoB: 2013-10-21 ( Medical record number)

effective: 2025-11-11 07:47:48+0000

value: Completed Electronically on HIVE

" }, "identifier" : [{ "system" : "https://fhir.nwgenomics.nhs.uk/Id/ResourceIdentifier", "value" : "R0A-1000162341-230029-IGENE", "assigner" : { "identifier" : { "system" : "https://fhir.nhs.uk/Id/ods-organization-code", "value" : "R0A" } } }], "status" : "final", "code" : { "coding" : [{ "system" : "https://fhir.nwgenomics.nhs.uk/CodeSystem/MFTQuestionIds", "code" : "230029", "display" : "Confirmation of Consent for Testing - MANDATORY Testing will not be performed without completed confirmation of consent" }] }, "subject" : { "reference" : "urn:uuid:2cc74315-590b-463e-a999-ef58d0255f5c" }, "effectiveDateTime" : "2025-11-11T07:47:48+00:00", "valueString" : "Completed Electronically on HIVE" } }, { "fullUrl" : "urn:uuid:c3da7c89-207e-4563-9977-a8198226f443", "resource" : { "resourceType" : "Observation", "language" : "en", "text" : { "status" : "generated", "div" : "

Generated Narrative: Observation

identifier: https://fhir.nwgenomics.nhs.uk/Id/ResourceIdentifier/R0A-1000162341-230037-IGENE

status: Final

code: Please Acknowledge That a DNA Sample Will be Stored in the Laboratory on Completion of Testing

subject: Lori Johnson Female, DoB: 2013-10-21 ( Medical record number)

effective: 2025-11-11 07:47:48+0000

value: Acknowledged

" }, "identifier" : [{ "system" : "https://fhir.nwgenomics.nhs.uk/Id/ResourceIdentifier", "value" : "R0A-1000162341-230037-IGENE", "assigner" : { "identifier" : { "system" : "https://fhir.nhs.uk/Id/ods-organization-code", "value" : "R0A" } } }], "status" : "final", "code" : { "coding" : [{ "system" : "https://fhir.nwgenomics.nhs.uk/CodeSystem/MFTQuestionIds", "code" : "230037", "display" : "Please Acknowledge That a DNA Sample Will be Stored in the Laboratory on Completion of Testing" }] }, "subject" : { "reference" : "urn:uuid:2cc74315-590b-463e-a999-ef58d0255f5c" }, "effectiveDateTime" : "2025-11-11T07:47:48+00:00", "valueString" : "Acknowledged" } }, { "fullUrl" : "urn:uuid:5af7d8ca-4d22-4d4d-bd8e-13300973070a", "resource" : { "resourceType" : "Observation", "language" : "en", "text" : { "status" : "generated", "div" : "

Generated Narrative: Observation

identifier: https://fhir.nwgenomics.nhs.uk/Id/ResourceIdentifier/R0A-1000162341-230039-IGENE

status: Final

code: Are you the Patient�s Consultant?

subject: Lori Johnson Female, DoB: 2013-10-21 ( Medical record number)

effective: 2025-11-11 07:47:48+0000

value: No

" }, "identifier" : [{ "system" : "https://fhir.nwgenomics.nhs.uk/Id/ResourceIdentifier", "value" : "R0A-1000162341-230039-IGENE", "assigner" : { "identifier" : { "system" : "https://fhir.nhs.uk/Id/ods-organization-code", "value" : "R0A" } } }], "status" : "final", "code" : { "coding" : [{ "system" : "https://fhir.nwgenomics.nhs.uk/CodeSystem/MFTQuestionIds", "code" : "230039", "display" : "Are you the Patient�s Consultant?" }] }, "subject" : { "reference" : "urn:uuid:2cc74315-590b-463e-a999-ef58d0255f5c" }, "effectiveDateTime" : "2025-11-11T07:47:48+00:00", "valueString" : "No" } }, { "fullUrl" : "urn:uuid:01887302-a78b-44e8-8a88-1b5d54b1819f", "resource" : { "resourceType" : "Observation", "language" : "en", "text" : { "status" : "generated", "div" : "

Generated Narrative: Observation

identifier: https://fhir.nwgenomics.nhs.uk/Id/ResourceIdentifier/R0A-1000162341-230049-IGENE

status: Final

code: Name of Supervising Consultant

subject: Lori Johnson Female, DoB: 2013-10-21 ( Medical record number)

effective: 2025-11-11 07:47:48+0000

value: PETERS, ROBERT

" }, "identifier" : [{ "system" : "https://fhir.nwgenomics.nhs.uk/Id/ResourceIdentifier", "value" : "R0A-1000162341-230049-IGENE", "assigner" : { "identifier" : { "system" : "https://fhir.nhs.uk/Id/ods-organization-code", "value" : "R0A" } } }], "status" : "final", "code" : { "coding" : [{ "system" : "https://fhir.nwgenomics.nhs.uk/CodeSystem/MFTQuestionIds", "code" : "230049", "display" : "Name of Supervising Consultant" }] }, "subject" : { "reference" : "urn:uuid:2cc74315-590b-463e-a999-ef58d0255f5c" }, "effectiveDateTime" : "2025-11-11T07:47:48+00:00", "valueString" : "PETERS, ROBERT" } }, { "fullUrl" : "urn:uuid:0621355d-1d67-4fb9-8935-ab09e9f39d0a", "resource" : { "resourceType" : "Observation", "language" : "en", "text" : { "status" : "generated", "div" : "

Generated Narrative: Observation

identifier: https://fhir.nwgenomics.nhs.uk/Id/ResourceIdentifier/R0A-1000162341-46098-0-

status: Final

code: Patient's Sex Assigned at Birth

subject: Lori Johnson Female, DoB: 2013-10-21 ( Medical record number)

value: F

" }, "identifier" : [{ "system" : "https://fhir.nwgenomics.nhs.uk/Id/ResourceIdentifier", "value" : "R0A-1000162341-46098-0-", "assigner" : { "identifier" : { "system" : "https://fhir.nhs.uk/Id/ods-organization-code", "value" : "R0A" } } }], "status" : "final", "code" : { "coding" : [{ "code" : "46098-0", "display" : "Patient's Sex Assigned at Birth" }] }, "subject" : { "reference" : "urn:uuid:2cc74315-590b-463e-a999-ef58d0255f5c" }, "valueString" : "F" } }, { "fullUrl" : "urn:uuid:41ed5392-b022-4eeb-9e94-33d15f3611a8", "resource" : { "resourceType" : "Specimen", "language" : "en", "text" : { "status" : "generated", "div" : "

Generated Narrative: Specimen

status: Unavailable

type: SAMPLE: BL

subject: Lori Johnson Female, DoB: 2013-10-21 ( Medical record number)

" }, "status" : "unavailable", "type" : { "coding" : [{ "code" : "SAMPLE: BL" }] }, "subject" : { "reference" : "urn:uuid:2cc74315-590b-463e-a999-ef58d0255f5c" } } }, { "fullUrl" : "urn:uuid:fbbf3f64-4fee-44de-ac11-da98a32ff1b4", "resource" : { "resourceType" : "ServiceRequest", "language" : "en", "text" : { "status" : "generated", "div" : "

Generated Narrative: ServiceRequest

identifier: Placer Identifier/1000162341

requisition: Placer Group Number/1000162341

status: Active

intent: Original Order

category: Molecular genetics procedure

code: Glial and Glioneuronal Tumour Differential, Paediatric, Multi-target NGS panel, copy number variant (1p, 19q, EGFR, ALK, C19MC, CDKN2A, FGFR1, KIAA1549, KIT, MYCN, PDGFRA, SMARCA4, SMARCB1, YAP1)

subject: Lori Johnson Female, DoB: 2013-10-21 ( Medical record number)

authoredOn: 2025-11-11 07:47:48+0000

requester: PractitionerRole

supportingInfo:

specimen: Specimen: status = unavailable; type = SAMPLE: BL

" }, "identifier" : [{ "type" : { "coding" : [{ "system" : "http://terminology.hl7.org/CodeSystem/v2-0203", "code" : "PLAC" }] }, "system" : "https://nw-gmsa.github.io/Id/PLAC", "value" : "1000162341", "assigner" : { "identifier" : { "system" : "https://fhir.nhs.uk/Id/ods-organization-code", "value" : "R0A" } } }], "requisition" : { "type" : { "coding" : [{ "system" : "http://terminology.hl7.org/CodeSystem/v2-0203", "code" : "PGN" }] }, "system" : "https://nw-gmsa.github.io/Id/PLAC", "value" : "1000162341", "assigner" : { "identifier" : { "system" : "https://fhir.nhs.uk/Id/ods-organization-code", "value" : "R0A" } } }, "status" : "active", "intent" : "original-order", "category" : [{ "coding" : [{ "system" : "http://snomed.info/sct", "code" : "116148004" }] }], "code" : { "coding" : [{ "system" : "https://fhir.nhs.uk/CodeSystem/England-GenomicTestDirectory", "code" : "M213.22" }] }, "subject" : { "reference" : "urn:uuid:2cc74315-590b-463e-a999-ef58d0255f5c" }, "authoredOn" : "2025-11-11T07:47:48+00:00", "requester" : { "reference" : "urn:uuid:1b9d42c1-ef8e-445a-a8d8-2a8a48aa1404" }, "supportingInfo" : [{ "reference" : "urn:uuid:9355d363-cc63-4bcb-a57f-6ef82dd0e6c3", "type" : "Observation" }, { "reference" : "urn:uuid:d2955ceb-4d4b-4ef7-9808-d4ad401036b7", "type" : "Observation" }, { "reference" : "urn:uuid:42a459ac-1540-434a-a65f-fe1d9dbc9c9f", "type" : "Observation" }, { "reference" : "urn:uuid:819110cc-da75-4428-a674-ca94328c45eb", "type" : "Observation" }, { "reference" : "urn:uuid:fc9bd807-fd99-49db-903c-2577b2e92b3e", "type" : "Observation" }, { "reference" : "urn:uuid:2336e28c-3bff-4220-82d9-7843dd6d981c", "type" : "Observation" }, { "reference" : "urn:uuid:01a0493d-b41d-4d5d-9223-fac8358a15fa", "type" : "Observation" }, { "reference" : "urn:uuid:c3da7c89-207e-4563-9977-a8198226f443", "type" : "Observation" }, { "reference" : "urn:uuid:5af7d8ca-4d22-4d4d-bd8e-13300973070a", "type" : "Observation" }, { "reference" : "urn:uuid:01887302-a78b-44e8-8a88-1b5d54b1819f", "type" : "Observation" }, { "reference" : "urn:uuid:0621355d-1d67-4fb9-8935-ab09e9f39d0a", "type" : "Observation" }], "specimen" : [{ "reference" : "urn:uuid:41ed5392-b022-4eeb-9e94-33d15f3611a8", "type" : "Specimen" }] } }, { "fullUrl" : "urn:uuid:af7d8130-2940-4743-beb3-1d904c14e3aa", "resource" : { "resourceType" : "ServiceRequest", "language" : "en", "text" : { "status" : "generated", "div" : "

Generated Narrative: ServiceRequest

identifier: Placer Identifier/1000162341-M213.13

requisition: Placer Group Number/1000162341

status: Active

intent: Order

category: Molecular genetics procedure

code: Glial and Glioneuronal Tumour Differential, Paediatric, C11orf95-RELA FISH/RT-PCR

subject: Lori Johnson Female, DoB: 2013-10-21 ( Medical record number)

authoredOn: 2025-11-11 07:47:48+0000

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