{
  "resourceType" : "Bundle",
  "id" : "Bundle-Message-FillerOrder",
  "meta" : {
    "profile" : ["https://fhir.nwgenomics.nhs.uk/StructureDefinition/BundleMessage"]
  },
  "language" : "en",
  "identifier" : {
    "value" : "728357"
  },
  "type" : "message",
  "timestamp" : "2026-07-02T08:44:38.631Z",
  "entry" : [{
    "fullUrl" : "urn:uuid:3bed1f74-173f-4841-b3c0-c112b8d53e12",
    "resource" : {
      "resourceType" : "MessageHeader",
      "language" : "en",
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"MessageHeader_null\"> </a><p class=\"res-header-id\"><b>Generated Narrative: MessageHeader </b></p><p><b>event</b>: <a href=\"http://terminology.hl7.org/7.2.0/CodeSystem-v2-0003.html#v2-0003-O21\">event: O21</a> (OML - Laboratory order)</p><h3>Destinations</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Endpoint</b></td><td><b>Receiver</b></td></tr><tr><td style=\"display: none\">*</td><td><a href=\"https://simplifier.net/resolve?scope=fhir.r4.ukcore.stu3.currentbuild@0.29.0-pre-release&amp;canonical=http://fhir.org/packages/fhir.r4.ukcore.stu3.currentbuild/https//fhir.mft.nhs.uk/Endpoint/RIE\">https//fhir.mft.nhs.uk/Endpoint/RIE</a></td><td>Identifier: <a href=\"NamingSystem-ods-organization-code-namingsystem.html\" title=\"The identifier system for an Organisation registered with the Organisation Data Service (ODS).\">ODS Organisation Code</a>/699X0</td></tr></table><p><b>sender</b>: Identifier: <a href=\"NamingSystem-ods-organization-code-namingsystem.html\" title=\"The identifier system for an Organisation registered with the Organisation Data Service (ODS).\">ODS Organisation Code</a>/699X0</p><h3>Sources</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Name</b></td><td><b>Software</b></td><td><b>Endpoint</b></td></tr><tr><td style=\"display: none\">*</td><td>IGENE</td><td>NW GLH</td><td><a href=\"https://simplifier.net/resolve?scope=fhir.r4.ukcore.stu3.currentbuild@0.29.0-pre-release&amp;canonical=https://fhir.nwgenomics.nhs.uk/Endpoint/IGENE\">https://fhir.nwgenomics.nhs.uk/Endpoint/IGENE</a></td></tr></table><p><b>focus</b>: <a href=\"Bundle-Bundle-Message-FillerOrder.html#urn-uuid-afae0544-f0d1-4cb1-afb9-572ee5dad285\">ServiceRequest ctDNA_M4</a></p></div>"
      },
      "eventCoding" : {
        "system" : "http://terminology.hl7.org/CodeSystem/v2-0003",
        "code" : "O21"
      },
      "destination" : [{
        "endpoint" : "https//fhir.mft.nhs.uk/Endpoint/RIE",
        "receiver" : {
          "identifier" : {
            "system" : "https://fhir.nhs.uk/Id/ods-organization-code",
            "value" : "699X0"
          }
        }
      }],
      "sender" : {
        "identifier" : {
          "system" : "https://fhir.nhs.uk/Id/ods-organization-code",
          "value" : "699X0"
        }
      },
      "source" : {
        "name" : "IGENE",
        "software" : "NW GLH",
        "endpoint" : "https://fhir.nwgenomics.nhs.uk/Endpoint/IGENE"
      },
      "focus" : [{
        "reference" : "urn:uuid:afae0544-f0d1-4cb1-afb9-572ee5dad285"
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  {
    "fullUrl" : "urn:uuid:17d826c4-911c-4b49-8910-fa079f50705f",
    "resource" : {
      "resourceType" : "Patient",
      "language" : "en",
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Patient_null\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Patient </b></p><p style=\"border: 1px #661aff solid; background-color: #e6e6ff; padding: 10px;\">Alicent DURHAM  Female, DoB: 1993-12-27 ( National Health Plan Identifier)</p><hr/><table class=\"grid\"><tr><td style=\"background-color: #f3f5da\" title=\"Other Ids (see the one above)\">Other Ids:</td><td colspan=\"3\"><ul><li>Patient internal identifier/336389</li><li>Medical record number/336577</li></ul></td></tr></table></div>"
      },
      "identifier" : [{
        "extension" : [{
          "url" : "https://fhir.hl7.org.uk/StructureDefinition/Extension-UKCore-NHSNumberVerificationStatus",
          "valueCodeableConcept" : {
            "coding" : [{
              "system" : "https://fhir.hl7.org.uk/CodeSystem/UKCore-NHSNumberVerificationStatusEngland",
              "code" : "05",
              "display" : "Trace needs to be resolved - (NHS number or patient detail conflict)"
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          }
        }],
        "type" : {
          "coding" : [{
            "system" : "http://terminology.hl7.org/CodeSystem/v2-0203",
            "code" : "NH"
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        },
        "system" : "https://fhir.nhs.uk/Id/nhs-number",
        "value" : "9737873998"
      },
      {
        "type" : {
          "coding" : [{
            "system" : "http://terminology.hl7.org/CodeSystem/v2-0203",
            "code" : "PI"
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        },
        "system" : "https://fhir.nwgenomics.nhs.uk/Identifier/IGENE-PatientIdentifier",
        "value" : "336389",
        "assigner" : {
          "identifier" : {
            "system" : "https://fhir.nhs.uk/Id/ods-organization-code",
            "value" : "699X0"
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      {
        "type" : {
          "coding" : [{
            "system" : "http://terminology.hl7.org/CodeSystem/v2-0203",
            "code" : "MR"
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        },
        "value" : "336577",
        "assigner" : {
          "identifier" : {
            "system" : "https://fhir.nhs.uk/Id/ods-organization-code",
            "value" : "RAE"
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        }
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      "name" : [{
        "family" : "DURHAM",
        "given" : ["Alicent"]
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      "gender" : "female",
      "birthDate" : "1993-12-27"
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  {
    "fullUrl" : "urn:uuid:b3cc579c-66b5-4fb1-91d4-dcc07d0f548c",
    "resource" : {
      "resourceType" : "Specimen",
      "language" : "en",
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Specimen_null\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Specimen </b></p><p><b>identifier</b>: Filler Identifier/S26-1K74</p><p><b>status</b>: Available</p><p><b>type</b>: <span title=\"Codes:{http://snomed.info/sct 119297000}\">Blood specimen</span></p><p><b>subject</b>: <a href=\"Bundle-Bundle-Message-FillerOrder.html#urn-uuid-17d826c4-911c-4b49-8910-fa079f50705f\">Alicent DURHAM  Female, DoB: 1993-12-27 ( National Health Plan Identifier)</a></p><h3>Collections</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Collected[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>2026-06-26</td></tr></table></div>"
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      "identifier" : [{
        "type" : {
          "coding" : [{
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        "system" : "https://fhir.nwgenomics.nhs.uk/Identifier/IGENE-SpecimenIdentifier",
        "value" : "S26-1K74",
        "assigner" : {
          "identifier" : {
            "system" : "https://fhir.nhs.uk/Id/ods-organization-code",
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      "type" : {
        "coding" : [{
          "system" : "http://snomed.info/sct",
          "code" : "119297000",
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        "reference" : "urn:uuid:17d826c4-911c-4b49-8910-fa079f50705f",
        "identifier" : {
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            "coding" : [{
              "system" : "http://terminology.hl7.org/CodeSystem/v2-0203",
              "code" : "NH"
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          },
          "system" : "https://fhir.nhs.uk/Id/nhs-number",
          "value" : "9737873998"
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      "collection" : {
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    "resource" : {
      "resourceType" : "ServiceRequest",
      "language" : "en",
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ServiceRequest_null\"> </a><p class=\"res-header-id\"><b>Generated Narrative: ServiceRequest </b></p><p><b>identifier</b>: Filler Identifier/R26-15F8</p><p><b>status</b>: Active</p><p><b>intent</b>: Original Order</p><p><b>category</b>: <span title=\"Codes:{http://snomed.info/sct 116148004}\">Molecular genetics procedure</span></p><p><b>code</b>: <span title=\"Codes:{https://fhir.nhs.uk/CodeSystem/England-GenomicTestDirectory M4.14}\">PACKAGE: M4.14 - Non-Small Cell Lung Cancer, Multi-target ctDNA combined Multi-target NGS panel - small variant (EGFR, ALK, BRAF, KRAS, MET exon 14 skipping and copy number variations) and structural variant (ROS1, RET, ALK, NTRK1, NTRK2, NTRK3, MET exon </span></p><p><b>subject</b>: <a href=\"Bundle-Bundle-Message-FillerOrder.html#urn-uuid-17d826c4-911c-4b49-8910-fa079f50705f\">Alicent DURHAM  Female, DoB: 1993-12-27 ( National Health Plan Identifier)</a></p><p><b>requester</b>: Identifier: <a href=\"NamingSystem-ods-organization-code-namingsystem.html\" title=\"The identifier system for an Organisation registered with the Organisation Data Service (ODS).\">ODS Organisation Code</a>/RAE</p><p><b>specimen</b>: <a href=\"Bundle-Bundle-Message-FillerOrder.html#urn-uuid-b3cc579c-66b5-4fb1-91d4-dcc07d0f548c\">Specimen: identifier = Filler Identifier; status = available; type = Blood specimen</a></p></div>"
      },
      "identifier" : [{
        "type" : {
          "coding" : [{
            "system" : "http://terminology.hl7.org/CodeSystem/v2-0203",
            "code" : "FILL"
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        },
        "system" : "https://fhir.nwgenomics.nhs.uk/Identifier/IGENE-ReferralIdentifier",
        "value" : "R26-15F8",
        "assigner" : {
          "identifier" : {
            "system" : "https://fhir.nhs.uk/Id/ods-organization-code",
            "value" : "699X0"
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        }
      }],
      "status" : "active",
      "intent" : "original-order",
      "category" : [{
        "coding" : [{
          "system" : "http://snomed.info/sct",
          "code" : "116148004"
        }]
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      "code" : {
        "coding" : [{
          "system" : "https://fhir.nhs.uk/CodeSystem/England-GenomicTestDirectory",
          "code" : "M4.14"
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        "text" : "PACKAGE: M4.14 - Non-Small Cell Lung Cancer, Multi-target ctDNA combined Multi-target NGS panel - small variant (EGFR, ALK, BRAF, KRAS, MET exon 14 skipping and copy number variations) and structural variant (ROS1, RET, ALK, NTRK1, NTRK2, NTRK3, MET exon "
      },
      "subject" : {
        "reference" : "urn:uuid:17d826c4-911c-4b49-8910-fa079f50705f",
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              "system" : "http://terminology.hl7.org/CodeSystem/v2-0203",
              "code" : "NH"
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          },
          "system" : "https://fhir.nhs.uk/Id/nhs-number",
          "value" : "9737873998"
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      "requester" : {
        "identifier" : {
          "system" : "https://fhir.nhs.uk/Id/ods-organization-code",
          "value" : "RAE"
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      "specimen" : [{
        "reference" : "urn:uuid:b3cc579c-66b5-4fb1-91d4-dcc07d0f548c",
        "type" : "Specimen"
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  {
    "fullUrl" : "urn:uuid:afae0544-f0d1-4cb1-afb9-572ee5dad285",
    "resource" : {
      "resourceType" : "ServiceRequest",
      "language" : "en",
      "text" : {
        "status" : "generated",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ServiceRequest_null\"> </a><p class=\"res-header-id\"><b>Generated Narrative: ServiceRequest </b></p><p><b>identifier</b>: Placer Identifier/T26-5AMV</p><p><b>basedOn</b>: <a href=\"Bundle-Bundle-Message-FillerOrder.html#urn-uuid-ae7d645c-f0e0-468b-a34f-a40aa2246874\">ServiceRequest Non-Small Cell Lung Cancer, Multi-target ctDNA combined Multi-target NGS panel, small variant (EGFR, ALK, BRAF, KRAS, MET exon 14 skipping and copy number variations) and structural variant (ROS1, RET, ALK, NTRK1, NTRK2, NTRK3, MET exon</a></p><p><b>requisition</b>: Placer Group Number/R26-15F8</p><p><b>status</b>: Active</p><p><b>intent</b>: Filler Order</p><p><b>category</b>: <span title=\"Codes:{http://snomed.info/sct 116148004}\">Molecular genetics procedure</span></p><p><b>code</b>: <span title=\"Codes:{https://fhir.nhs.uk/CodeSystem/England-GenomicTestDirectory ctDNA_M4}\">PACKAGE: M4.14 - Non-Small Cell Lung Cancer, Multi-target ctDNA combined Multi-target NGS panel - small variant (EGFR, ALK, BRAF, KRAS, MET exon 14 skipping and copy number variations) and structural variant (ROS1, RET, ALK, NTRK1, NTRK2, NTRK3, MET exon </span></p><p><b>subject</b>: <a href=\"Bundle-Bundle-Message-FillerOrder.html#urn-uuid-17d826c4-911c-4b49-8910-fa079f50705f\">Alicent DURHAM  Female, DoB: 1993-12-27 ( National Health Plan Identifier)</a></p><p><b>authoredOn</b>: 2026-06-30</p><p><b>requester</b>: Identifier: <a href=\"NamingSystem-ods-organization-code-namingsystem.html\" title=\"The identifier system for an Organisation registered with the Organisation Data Service (ODS).\">ODS Organisation Code</a>/699X0</p><p><b>performer</b>: Identifier: <a href=\"NamingSystem-ods-organization-code-namingsystem.html\" title=\"The identifier system for an Organisation registered with the Organisation Data Service (ODS).\">ODS Organisation Code</a>/699X0</p><p><b>specimen</b>: <a href=\"Bundle-Bundle-Message-FillerOrder.html#urn-uuid-b3cc579c-66b5-4fb1-91d4-dcc07d0f548c\">Specimen: identifier = Filler Identifier; status = available; type = Blood specimen</a></p></div>"
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            "system" : "http://terminology.hl7.org/CodeSystem/v2-0203",
            "code" : "PLAC"
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        },
        "system" : "https://fhir.nwgenomics.nhs.uk/Identifier/IGENE-TestIdentifier",
        "value" : "T26-5AMV",
        "assigner" : {
          "identifier" : {
            "system" : "https://fhir.nhs.uk/Id/ods-organization-code",
            "value" : "699X0"
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      "basedOn" : [{
        "reference" : "urn:uuid:ae7d645c-f0e0-468b-a34f-a40aa2246874"
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      "requisition" : {
        "type" : {
          "coding" : [{
            "system" : "http://terminology.hl7.org/CodeSystem/v2-0203",
            "code" : "PGN"
          }]
        },
        "system" : "https://fhir.nwgenomics.nhs.uk/Identifier/IGENE-ReferralIdentifier",
        "value" : "R26-15F8",
        "assigner" : {
          "identifier" : {
            "system" : "https://fhir.nhs.uk/Id/ods-organization-code",
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          }
        }
      },
      "status" : "active",
      "intent" : "filler-order",
      "category" : [{
        "coding" : [{
          "system" : "http://snomed.info/sct",
          "code" : "116148004"
        }]
      }],
      "code" : {
        "coding" : [{
          "system" : "https://fhir.nhs.uk/CodeSystem/England-GenomicTestDirectory",
          "code" : "ctDNA_M4"
        }],
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      "subject" : {
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          "value" : "9737873998"
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      "authoredOn" : "2026-06-30",
      "requester" : {
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      "performer" : [{
        "identifier" : {
          "system" : "https://fhir.nhs.uk/Id/ods-organization-code",
          "value" : "699X0"
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      "specimen" : [{
        "reference" : "urn:uuid:b3cc579c-66b5-4fb1-91d4-dcc07d0f548c",
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}