{ "resourceType" : "Bundle", "id" : "GenomicsOrderMessage-ctDNA", "meta" : { "profile" : ["https://fhir.nwgenomics.nhs.uk/StructureDefinition/BundleMessage"] }, "language" : "en", "identifier" : { "system" : "urn:ietf:rfc:3986", "value" : "urn:uuid:1aa724a8-981e-488e-9e6b-7a73e7c3c07a" }, "type" : "message", "timestamp" : "2025-10-14T15:59:16+00:00", "entry" : [{ "fullUrl" : "urn:uuid:72d8c754-ebd0-4e3c-b6e1-4d99cadb7f50", "resource" : { "resourceType" : "MessageHeader", "id" : "MessageHeaderO21ctDNA", "meta" : { "lastUpdated" : "2026-07-13T10:39:26+00:00", "profile" : ["https://fhir.nwgenomics.nhs.uk/StructureDefinition/MessageHeader"] }, "language" : "en", "text" : { "status" : "generated", "div" : "

Generated Narrative: MessageHeader MessageHeaderO21ctDNA

Last updated: 2026-07-13 10:39:26+0000

Profile: Document Message (MessageHeader)

event: event: O21 (OML - Laboratory order)

Destinations

-EndpointReceiver
*https://fhir.nwgenomics.nhs.uk/Endpoint/NEYAWSSQSNEY GMSA (Identifier: ODS Organisation Code/699N0)

sender: Identifier: ODS Organisation Code/699X0

Sources

-SoftwareEndpoint
*NW GMSAhttps://fhir.nwgenomics.nhs.uk/Endpoint/iGene

focus: ServiceRequest Non-Small Cell Lung Cancer, Multi-target ctDNA combined Multi-target NGS panel, small variant (EGFR, ALK, BRAF, KRAS, MET exon 14 skipping and copy number variations) and structural variant (ROS1, RET, ALK, NTRK1, NTRK2, NTRK3, MET exon

" }, "eventCoding" : { "system" : "http://terminology.hl7.org/CodeSystem/v2-0003", "code" : "O21" }, "destination" : [{ "endpoint" : "https://fhir.nwgenomics.nhs.uk/Endpoint/NEYAWSSQS", "receiver" : { "identifier" : { "system" : "https://fhir.nhs.uk/Id/ods-organization-code", "value" : "699N0" }, "display" : "NEY GMSA" } }], "sender" : { "identifier" : { "system" : "https://fhir.nhs.uk/Id/ods-organization-code", "value" : "699X0" } }, "source" : { "software" : "NW GMSA", "endpoint" : "https://fhir.nwgenomics.nhs.uk/Endpoint/iGene" }, "focus" : [{ "reference" : "urn:uuid:6e26d6b3-490e-4348-9d6c-37281567d6ec", "type" : "ServiceRequest" }] } }, { "fullUrl" : "urn:uuid:2160525b-0168-4f40-8ebf-9b053052a62c", "resource" : { "resourceType" : "Patient", "id" : "Patient-Sheffield", "meta" : { "profile" : ["https://fhir.nwgenomics.nhs.uk/StructureDefinition/Patient"] }, "language" : "en", "text" : { "status" : "generated", "div" : "

Generated Narrative: Patient Patient-Sheffield

Profile: Patient

Theon SHEFFIELD (official) Male, DoB: 1986-09-12 ( Patient internal identifier)

Active:true
Other Id:National Health Plan Identifier/9737873858\u00a0(use:\u00a0official,\u00a0)
Contact DetailSPITAL STREET SHEFFIELD S3 9LB (home)
Links:
" }, "identifier" : [{ "use" : "official", "type" : { "coding" : [{ "system" : "http://terminology.hl7.org/CodeSystem/v2-0203", "code" : "NH" }] }, "system" : "https://fhir.nhs.uk/Id/nhs-number", "value" : "9737873858" }, { "type" : { "coding" : [{ "system" : "http://terminology.hl7.org/CodeSystem/v2-0203", "code" : "PI" }] }, "value" : "336292", "assigner" : { "identifier" : { "system" : "https://fhir.nhs.uk/Id/ods-organization-code", "value" : "699X0" } } }], "active" : true, "name" : [{ "use" : "official", "family" : "SHEFFIELD", "given" : ["Theon"] }], "gender" : "male", "birthDate" : "1986-09-12", "address" : [{ "use" : "home", "type" : "both", "line" : ["SPITAL STREET"], "city" : "SHEFFIELD", "postalCode" : "S3 9LB" }], "generalPractitioner" : [{ "identifier" : { "system" : "https://fhir.nhs.uk/Id/ods-organization-code", "value" : "C88622" }, "display" : "Sheffield Medical Centre" }] } }, { "fullUrl" : "urn:uuid:6e26d6b3-490e-4348-9d6c-37281567d6ec", "resource" : { "resourceType" : "ServiceRequest", "id" : "ServiceRequest-ctDNA", "meta" : { "versionId" : "1.0", "profile" : ["https://fhir.nwgenomics.nhs.uk/StructureDefinition/ServiceRequest"] }, "language" : "en", "text" : { "status" : "generated", "div" : "

Generated Narrative: ServiceRequest ServiceRequest-ctDNA

version: 1.0

Profile: ServiceRequest

identifier: Filler Identifier/T26-59XG

requisition: Placer Group Number/R26-15AY

status: Active

intent: Order

category: Molecular genetics procedure

code: Non-Small Cell Lung Cancer, Multi-target ctDNA combined Multi-target NGS panel, small variant (EGFR, ALK, BRAF, KRAS, MET exon 14 skipping and copy number variations) and structural variant (ROS1, RET, ALK, NTRK1, NTRK2, NTRK3, MET exon

subject: Theon SHEFFIELD

requester: Identifier: ODS Organisation Code/RHQ

performer: Identifier: ODS Organisation Code/699X0

reasonCode: M4

specimen: Specimen: identifier = Filler Identifier; status = available; type = Blood specimen

" }, "identifier" : [{ "type" : { "coding" : [{ "system" : "http://terminology.hl7.org/CodeSystem/v2-0203", "code" : "FILL" }] }, "system" : "https://fhir.nwgenomics.nhs.uk/iGene/ReportIdentifier", "value" : "T26-59XG", "assigner" : { "identifier" : { "system" : "https://fhir.nhs.uk/Id/ods-organization-code", "value" : "699X0" } } }], "requisition" : { "type" : { "coding" : [{ "system" : "http://terminology.hl7.org/CodeSystem/v2-0203", "code" : "PGN" }] }, "system" : "https://fhir.nwgenomics.nhs.uk/iGene/ReferralIdentifier", "value" : "R26-15AY", "assigner" : { "identifier" : { "system" : "https://fhir.nhs.uk/Id/ods-organization-code", "value" : "699X0" } } }, "status" : "active", "intent" : "order", "category" : [{ "coding" : [{ "system" : "http://snomed.info/sct", "code" : "116148004", "display" : "Molecular genetics procedure" }] }], "code" : { "coding" : [{ "system" : "https://fhir.nhs.uk/CodeSystem/England-GenomicTestDirectory", "code" : "M4.14" }] }, "subject" : { "reference" : "urn:uuid:2160525b-0168-4f40-8ebf-9b053052a62c", "identifier" : { "system" : "https://fhir.nhs.uk/Id/nhs-number", "value" : "9737873858" }, "display" : "Theon SHEFFIELD" }, "requester" : { "type" : "Organization", "identifier" : { "system" : "https://fhir.nhs.uk/Id/ods-organization-code", "value" : "RHQ" } }, "performer" : [{ "type" : "Organization", "identifier" : { "system" : "https://fhir.nhs.uk/Id/ods-organization-code", "value" : "699X0" } }], "reasonCode" : [{ "coding" : [{ "system" : "https://fhir.nwgenomics.nhs.uk/CodeSystem/GenomicClinicalIndication", "code" : "M4" }] }], "specimen" : [{ "reference" : "urn:uuid:b930b4c4-327a-4728-8bb9-f90061914cc5" }] } }, { "fullUrl" : "urn:uuid:b930b4c4-327a-4728-8bb9-f90061914cc5", "resource" : { "resourceType" : "Specimen", "id" : "Specimen-ctDNA", "meta" : { "versionId" : "1.0", "profile" : ["https://fhir.nwgenomics.nhs.uk/StructureDefinition/Specimen"] }, "language" : "en", "text" : { "status" : "generated", "div" : "

Generated Narrative: Specimen Specimen-ctDNA

version: 1.0

Profile: Specimen

identifier: Filler Identifier/S26-1K1Q

status: Available

type: Blood specimen

subject: Theon SHEFFIELD

Collections

-Collected[x]
*2026-06-29
" }, "identifier" : [{ "type" : { "coding" : [{ "system" : "http://terminology.hl7.org/CodeSystem/v2-0203", "code" : "FILL" }] }, "system" : "https://fhir.nwgenomics.nhs.uk/iGene/SpecimenIdentifier", "value" : "S26-1K1Q", "assigner" : { "identifier" : { "system" : "https://fhir.nhs.uk/Id/ods-organization-code", "value" : "699X0" } } }], "status" : "available", "type" : { "coding" : [{ "system" : "http://snomed.info/sct", "code" : "119297000", "display" : "Blood specimen" }] }, "subject" : { "reference" : "urn:uuid:2160525b-0168-4f40-8ebf-9b053052a62c", "identifier" : { "system" : "https://fhir.nhs.uk/Id/nhs-number", "value" : "9737873858" }, "display" : "Theon SHEFFIELD" }, "collection" : { "collectedDateTime" : "2026-06-29" } } }] }