{ "resourceType" : "Questionnaire", "id" : "BCRABLResultPanel", "meta" : { "profile" : ["https://fhir.nwgenomics.nhs.uk/StructureDefinition/NWQuestionnaire"] }, "language" : "en", "text" : { "status" : "extensions", "div" : "

Generated Narrative: Questionnaire BCRABLResultPanel

Profile: Questionnaire

\r\n\r\n\r\n\r\n\r\n\r\n\r\n\r\n\r\n\r\n\r\n\r\n\r\n\r\n\r\n\r\n\r\n\r\n\r\n\r\n\r\n\r\n\r\n\r\n\r\n\r\n\r\n\r\n\r\n\r\n
LinkIDTextCardinalityTypeDescription & Constraints\"doco\"
\".\"\".\" Result panel for BCR-ABL1 monitoring (chronic myeloid leukaemia), capturing a\nCepheid-class ASTM-communicating analyser's result as a [Laboratory Analyte\nResult](StructureDefinition-LaboratoryAnalyteResult.html) `Observation` - see\n[BCR-ABL Monitoring](BCRABLMonitoring.html).\n\n`item.definition` and `item.code` are inferred directly from this IG's own\nexample `Observation`s -\n[Observation-BCRABL-Valid](Observation-BCRABL-Valid.html),\n[Observation-BCRABL-Invalid](Observation-BCRABL-Invalid.html) and\n`Observation-LAR-BCRABL` (`input/fsh/Examples/BCRABL/`) - not just the\n[data mapping table](LaboratoryAnalyteResult.html#data-mapping): the local\n`Cepheid` CodeSystem component codes below (`BCR-ABL&`, `ABL&Ct`, etc.) are the\nexact codes those examples use, and the two examples together show both a\nnormal result and the `dataAbsentReason` shape used when a value is invalid/out\nof range.Questionnairehttps://fhir.nwgenomics.nhs.uk/Questionnaire/BCRABLResultPanel#2.2.0
\".\"\".\"\".\" ResultBCR-ABL Result0..1groupDefinition: Observation
\".\"\".\"\".\"\".\" LN/89061-6NHS Number0..1stringDefinition: Observation.subject.identifier
\".\"\".\"\".\"\".\" Cepheid/AssayCodeAnalyte Code1..1stringDefinition: Observation.code
\".\"\".\"\".\"\".\"\".\" Cepheid/AssayCode-designNoteObservation.code carries two codings: the Cepheid analyte code (e.g. BCRABL) and, per Observation-BCRABL-Valid, the specific Cepheid cartridge/assay code (e.g. Xpert-BCR-ABL-Ultra-G2).0..1display
\".\"\".\"\".\"\".\" Cepheid/TestStartTest Start DateTime0..1dateTimeDefinition: Observation.effectivePeriod.start
\".\"\".\"\".\"\".\" Cepheid/TestEndTest End DateTime0..1dateTimeDefinition: Observation.effectivePeriod.end
\".\"\".\"\".\"\".\" Cepheid/PerformerPerformer0..1stringDefinition: Observation.performer
\".\"\".\"\".\"\".\"\".\" Cepheid/Performer-designNoteBoth examples carry two performers: the performing laboratory (Organization, ODS code) and the analyst (practitioner display text only).0..1display
\".\"\".\"\".\"\".\" OBR-25Result Status0..1choiceDefinition: Observation.status
\".\"\".\"\".\"\".\"\".\" OBR-25-designNoteBoth examples use status = final (F).0..1display
\".\"\".\"\".\"\".\" Cepheid/ReferenceRangeReference Range0..1stringDefinition: Observation.referenceRange.text
\".\"\".\"\".\"\".\"\".\" Cepheid/ReferenceRange-designNoteBoth examples use text-only "0.0030-55.00", not a coded low/high Quantity.0..1display
\".\"\".\"\".\"\".\" Cepheid/ValueAnalyte Result (%IS)0..1decimalDefinition: Observation.valueQuantity.value
\".\"\".\"\".\"\".\"\".\" Cepheid/Value-designNoteObservation-BCRABL-Valid populates this (0.011); Observation-BCRABL-Invalid omits it entirely and populates Value Absent below instead - the two are mutually exclusive in both examples.0..1display
\".\"\".\"\".\"\".\" Cepheid/ValueAbsentValue Absent0..1stringDefinition: Observation.dataAbsentReason.text
\".\"\".\"\".\"\".\"\".\" Cepheid/ValueAbsent-designNoteObservation-BCRABL-Invalid uses this for an out-of-range result: dataAbsentReason.text = "POSITIVE [Above upper LoQ]".0..1display
\".\"\".\"\".\"\".\" Cepheid/DeviceIdentifierDevice Identifier0..1stringDefinition: Observation.device.identifier
\".\"\".\"\".\"\".\"\".\" Cepheid/DeviceIdentifier-designNoteBoth examples carry the full Cepheid instrument/run identifier string (e.g. "20901225~08699~114262192~604297~700039~WinDev2006Eval") as a single identifier value, not decomposed into its component parts.0..1display
\".\"\".\"\".\"\".\" ResultDetailResult Detail0..1groupDefinition: Observation.component
\".\"\".\"\".\"\".\"\".\" Cepheid/MRMR0..1decimalDefinition: Observation.component.valueQuantity
\".\"\".\"\".\"\".\"\".\"\".\" Cepheid/MR-designNotePresent (valueQuantity) in Observation-BCRABL-Valid; present but with no value[x] at all in Observation-BCRABL-Invalid - the component itself is still listed.0..1display
\".\"\".\"\".\"\".\"\".\" Cepheid/BCR-ABLBCR-ABL Analyte Result0..1stringDefinition: Observation.component.valueString
\".\"\".\"\".\"\".\"\".\" Cepheid/BCR-ABL-CtBCR-ABL Ct0..1decimalDefinition: Observation.component.valueQuantity
\".\"\".\"\".\"\".\"\".\" Cepheid/BCR-ABL-EndPtBCR-ABL EndPt0..1decimalDefinition: Observation.component.valueQuantity
\".\"\".\"\".\"\".\"\".\" Cepheid/BCR-ABL-DeltaCtBCR-ABL Target Delta Ct0..1decimalDefinition: Observation.component.valueQuantity
\".\"\".\"\".\"\".\"\".\" Cepheid/ABLABL Probe Check Result0..1stringDefinition: Observation.component.valueString
\".\"\".\"\".\"\".\"\".\" Cepheid/ABL-CtABL Ct0..1decimalDefinition: Observation.component.valueQuantity
\".\"\".\"\".\"\".\"\".\" Cepheid/ABL-EndPtABL EndPt0..1decimalDefinition: Observation.component.valueQuantity
\".\"\".\"\".\"\".\"\".\"\".\" Cepheid/ABL-EndPt-designNoteThe BCRABL Result Detail table (see LaboratoryAnalyteResult.html and\nBCRABLMonitoring.html) also lists ABL_Probe_Check_Result,\nBCR-ABL_Probe_Check_Result as separate rows and a few "??"-flagged local\ncodes - neither example Observation actually populates a distinct\nProbe_Check_Result component beyond ABL&/BCR-ABL&, so this Questionnaire\nonly models the 8 components genuinely present in the example data.0..1display

\"doco\" Documentation for this format
" }, "extension" : [{ "url" : "http://hl7.org/fhir/StructureDefinition/artifact-versionAlgorithm", "valueCoding" : { "system" : "http://hl7.org/fhir/version-algorithm", "code" : "semver" } }], "url" : "https://fhir.nwgenomics.nhs.uk/Questionnaire/BCRABLResultPanel", "version" : "2.2.0", "title" : "BCR-ABL Monitoring Result Panel", "status" : "active", "date" : "2026-09-20T05:53:36+00:00", "publisher" : "NHS North West Genomics", "contact" : [{ "telecom" : [{ "system" : "url", "value" : "https://www.nwgenomics.nhs.uk/contact-us" }] }], "description" : "Result panel for BCR-ABL1 monitoring (chronic myeloid leukaemia), capturing a\nCepheid-class ASTM-communicating analyser's result as a [Laboratory Analyte\nResult](StructureDefinition-LaboratoryAnalyteResult.html) `Observation` - see\n[BCR-ABL Monitoring](BCRABLMonitoring.html).\n\n`item.definition` and `item.code` are inferred directly from this IG's own\nexample `Observation`s -\n[Observation-BCRABL-Valid](Observation-BCRABL-Valid.html),\n[Observation-BCRABL-Invalid](Observation-BCRABL-Invalid.html) and\n`Observation-LAR-BCRABL` (`input/fsh/Examples/BCRABL/`) - not just the\n[data mapping table](LaboratoryAnalyteResult.html#data-mapping): the local\n`Cepheid` CodeSystem component codes below (`BCR-ABL&`, `ABL&Ct`, etc.) are the\nexact codes those examples use, and the two examples together show both a\nnormal result and the `dataAbsentReason` shape used when a value is invalid/out\nof range.", "jurisdiction" : [{ "coding" : [{ "system" : "urn:iso:std:iso:3166", "code" : "GB", "display" : "United Kingdom of Great Britain and Northern Ireland" }] }], "code" : [{ "system" : "http://loinc.org", "code" : "69380-4", "display" : "t(9;22)(q34.1;q11)(ABL1,BCR) b2a2+b3a2 fusion transcript/control transcript (International Scale) [# Ratio] in Blood or Tissue by Molecular genetics method" }], "item" : [{ "linkId" : "Result", "definition" : "http://hl7.org/fhir/StructureDefinition/Observation#Observation", "text" : "BCR-ABL Result", "type" : "group", "item" : [{ "linkId" : "LN/89061-6", "definition" : "http://hl7.org/fhir/StructureDefinition/Observation#Observation.subject.identifier", "code" : [{ "system" : "http://loinc.org", "code" : "89061-6" }], "text" : "NHS Number", "type" : "string" }, { "linkId" : "Cepheid/AssayCode", "definition" : "http://hl7.org/fhir/StructureDefinition/Observation#Observation.code", "code" : [{ "system" : "https://fhir.nwgenomics.nhs.uk/CodeSystem/Cepheid", "code" : "BCRABL" }], "text" : "Analyte Code", "type" : "string", "required" : true, "item" : [{ "extension" : [{ "url" : "http://hl7.org/fhir/StructureDefinition/questionnaire-itemControl", "valueCodeableConcept" : { "coding" : [{ "system" : "http://hl7.org/fhir/questionnaire-item-control", "code" : "help" }] } }], "linkId" : "Cepheid/AssayCode-designNote", "text" : "Observation.code carries two codings: the Cepheid analyte code (e.g. BCRABL) and, per Observation-BCRABL-Valid, the specific Cepheid cartridge/assay code (e.g. Xpert-BCR-ABL-Ultra-G2).", "type" : "display" }] }, { "linkId" : "Cepheid/TestStart", "definition" : "http://hl7.org/fhir/StructureDefinition/Observation#Observation.effectivePeriod.start", "text" : "Test Start DateTime", "type" : "dateTime" }, { "linkId" : "Cepheid/TestEnd", "definition" : "http://hl7.org/fhir/StructureDefinition/Observation#Observation.effectivePeriod.end", "text" : "Test End DateTime", "type" : "dateTime" }, { "linkId" : "Cepheid/Performer", "definition" : "http://hl7.org/fhir/StructureDefinition/Observation#Observation.performer", "text" : "Performer", "type" : "string", "item" : [{ "extension" : [{ "url" : "http://hl7.org/fhir/StructureDefinition/questionnaire-itemControl", "valueCodeableConcept" : { "coding" : [{ "system" : "http://hl7.org/fhir/questionnaire-item-control", "code" : "help" }] } }], "linkId" : "Cepheid/Performer-designNote", "text" : "Both examples carry two performers: the performing laboratory (Organization, ODS code) and the analyst (practitioner display text only).", "type" : "display" }] }, { "linkId" : "OBR-25", "definition" : "http://hl7.org/fhir/StructureDefinition/Observation#Observation.status", "code" : [{ "system" : "http://loinc.org", "code" : "89264-8", "display" : "Overall Interpretation of Study" }], "text" : "Result Status", "type" : "choice", "item" : [{ "extension" : [{ "url" : "http://hl7.org/fhir/StructureDefinition/questionnaire-itemControl", "valueCodeableConcept" : { "coding" : [{ "system" : "http://hl7.org/fhir/questionnaire-item-control", "code" : "help" }] } }], "linkId" : "OBR-25-designNote", "text" : "Both examples use status = final (F).", "type" : "display" }] }, { "linkId" : "Cepheid/ReferenceRange", "definition" : "http://hl7.org/fhir/StructureDefinition/Observation#Observation.referenceRange.text", "text" : "Reference Range", "type" : "string", "item" : [{ "extension" : [{ "url" : "http://hl7.org/fhir/StructureDefinition/questionnaire-itemControl", "valueCodeableConcept" : { "coding" : [{ "system" : "http://hl7.org/fhir/questionnaire-item-control", "code" : "help" }] } }], "linkId" : "Cepheid/ReferenceRange-designNote", "text" : "Both examples use text-only \"0.0030-55.00\", not a coded low/high Quantity.", "type" : "display" }] }, { "linkId" : "Cepheid/Value", "definition" : "http://hl7.org/fhir/StructureDefinition/Observation#Observation.valueQuantity.value", "text" : "Analyte Result (%IS)", "type" : "decimal", "item" : [{ "extension" : [{ "url" : "http://hl7.org/fhir/StructureDefinition/questionnaire-itemControl", "valueCodeableConcept" : { "coding" : [{ "system" : "http://hl7.org/fhir/questionnaire-item-control", "code" : "help" }] } }], "linkId" : "Cepheid/Value-designNote", "text" : "Observation-BCRABL-Valid populates this (0.011); Observation-BCRABL-Invalid omits it entirely and populates Value Absent below instead - the two are mutually exclusive in both examples.", "type" : "display" }] }, { "linkId" : "Cepheid/ValueAbsent", "definition" : "http://hl7.org/fhir/StructureDefinition/Observation#Observation.dataAbsentReason.text", "text" : "Value Absent", "type" : "string", "item" : [{ "extension" : [{ "url" : "http://hl7.org/fhir/StructureDefinition/questionnaire-itemControl", "valueCodeableConcept" : { "coding" : [{ "system" : "http://hl7.org/fhir/questionnaire-item-control", "code" : "help" }] } }], "linkId" : "Cepheid/ValueAbsent-designNote", "text" : "Observation-BCRABL-Invalid uses this for an out-of-range result: dataAbsentReason.text = \"POSITIVE [Above upper LoQ]\".", "type" : "display" }] }, { "linkId" : "Cepheid/DeviceIdentifier", "definition" : "http://hl7.org/fhir/StructureDefinition/Observation#Observation.device.identifier", "text" : "Device Identifier", "type" : "string", "item" : [{ "extension" : [{ "url" : "http://hl7.org/fhir/StructureDefinition/questionnaire-itemControl", "valueCodeableConcept" : { "coding" : [{ "system" : "http://hl7.org/fhir/questionnaire-item-control", "code" : "help" }] } }], "linkId" : "Cepheid/DeviceIdentifier-designNote", "text" : "Both examples carry the full Cepheid instrument/run identifier string (e.g. \"20901225~08699~114262192~604297~700039~WinDev2006Eval\") as a single identifier value, not decomposed into its component parts.", "type" : "display" }] }, { "linkId" : "ResultDetail", "definition" : "http://hl7.org/fhir/StructureDefinition/Observation#Observation.component", "text" : "Result Detail", "type" : "group", "item" : [{ "linkId" : "Cepheid/MR", "definition" : "http://hl7.org/fhir/StructureDefinition/Observation#Observation.component.valueQuantity", "code" : [{ "system" : "https://fhir.nwgenomics.nhs.uk/CodeSystem/Cepheid", "code" : "&MR" }], "text" : "MR", "type" : "decimal", "item" : [{ "extension" : [{ "url" : "http://hl7.org/fhir/StructureDefinition/questionnaire-itemControl", "valueCodeableConcept" : { "coding" : [{ "system" : "http://hl7.org/fhir/questionnaire-item-control", "code" : "help" }] } }], "linkId" : "Cepheid/MR-designNote", "text" : "Present (valueQuantity) in Observation-BCRABL-Valid; present but with no value[x] at all in Observation-BCRABL-Invalid - the component itself is still listed.", "type" : "display" }] }, { "linkId" : "Cepheid/BCR-ABL", "definition" : "http://hl7.org/fhir/StructureDefinition/Observation#Observation.component.valueString", "code" : [{ "system" : "https://fhir.nwgenomics.nhs.uk/CodeSystem/Cepheid", "code" : "BCR-ABL&" }], "text" : "BCR-ABL Analyte Result", "type" : "string" }, { "linkId" : "Cepheid/BCR-ABL-Ct", "definition" : "http://hl7.org/fhir/StructureDefinition/Observation#Observation.component.valueQuantity", "code" : [{ "system" : "https://fhir.nwgenomics.nhs.uk/CodeSystem/Cepheid", "code" : "BCR-ABL&Ct" }], "text" : "BCR-ABL Ct", "type" : "decimal" }, { "linkId" : "Cepheid/BCR-ABL-EndPt", "definition" : "http://hl7.org/fhir/StructureDefinition/Observation#Observation.component.valueQuantity", "code" : [{ "system" : "https://fhir.nwgenomics.nhs.uk/CodeSystem/Cepheid", "code" : "BCR-ABL&EndPt" }], "text" : "BCR-ABL EndPt", "type" : "decimal" }, { "linkId" : "Cepheid/BCR-ABL-DeltaCt", "definition" : "http://hl7.org/fhir/StructureDefinition/Observation#Observation.component.valueQuantity", "code" : [{ "system" : "https://fhir.nwgenomics.nhs.uk/CodeSystem/Cepheid", "code" : "BCR-ABL&Delta Ct" }], "text" : "BCR-ABL Target Delta Ct", "type" : "decimal" }, { "linkId" : "Cepheid/ABL", "definition" : "http://hl7.org/fhir/StructureDefinition/Observation#Observation.component.valueString", "code" : [{ "system" : "https://fhir.nwgenomics.nhs.uk/CodeSystem/Cepheid", "code" : "ABL&" }], "text" : "ABL Probe Check Result", "type" : "string" }, { "linkId" : "Cepheid/ABL-Ct", "definition" : "http://hl7.org/fhir/StructureDefinition/Observation#Observation.component.valueQuantity", "code" : [{ "system" : "https://fhir.nwgenomics.nhs.uk/CodeSystem/Cepheid", "code" : "ABL&Ct" }], "text" : "ABL Ct", "type" : "decimal" }, { "linkId" : "Cepheid/ABL-EndPt", "definition" : "http://hl7.org/fhir/StructureDefinition/Observation#Observation.component.valueQuantity", "code" : [{ "system" : "https://fhir.nwgenomics.nhs.uk/CodeSystem/Cepheid", "code" : "ABL&EndPt" }], "text" : "ABL EndPt", "type" : "decimal", "item" : [{ "extension" : [{ "url" : "http://hl7.org/fhir/StructureDefinition/questionnaire-itemControl", "valueCodeableConcept" : { "coding" : [{ "system" : "http://hl7.org/fhir/questionnaire-item-control", "code" : "help" }] } }], "linkId" : "Cepheid/ABL-EndPt-designNote", "text" : "The BCRABL Result Detail table (see LaboratoryAnalyteResult.html and\nBCRABLMonitoring.html) also lists ABL_Probe_Check_Result,\nBCR-ABL_Probe_Check_Result as separate rows and a few \"??\"-flagged local\ncodes - neither example Observation actually populates a distinct\nProbe_Check_Result component beyond ABL&/BCR-ABL&, so this Questionnaire\nonly models the 8 components genuinely present in the example data.", "type" : "display" }] }] }] }] }