NHS North West Genomics
2.0.0 - ci-build
GB
NHS North West Genomics
2.0.0 - ci-build
GB
NHS North West Genomics - Local Development build (v2.0.0) built by the FHIR (HL7® FHIR® Standard) Build Tools. See the Directory of published versions
| Official URL: https://fhir.nwgenomics.nhs.uk/ImplementationGuide/fhir.nwgenomics.nhs.uk | Version: 2.0.0 | |||
| Draft as of 2026-05-30 | Computable Name: NWGMSA | |||
Diagnostic testing is essential to modern clinical care, offering objective information that supports decision-making at every stage of a patient’s journey—from initial evaluation to long-term monitoring and assessment of outcomes.
Genomic diagnostic testing contributes to this process by examining a patient’s DNA or RNA to detect genetic variations that influence disease susceptibility, diagnosis, treatment choices, and prognosis. By delivering highly specific and personalised insights, genomic testing improves the accuracy and effectiveness of clinical management.
NHS North West Genomics is a new regional NHS service that consolidates clinical genomic testing across the North West of England. Although the service is delivered regionally, it also processes genomic test requests from across the UK. The service is hosted by Manchester University NHS Foundation Trust.
As part of the service transition, existing systems for electronic test ordering and reporting will be enhanced through the introduction of a Regional Orchestration Engine (ROE) and a Genomic Data Platform. These components enable seamless data exchange between local clinical systems and regional genomic laboratory services.
graph TD
User[<b>User Requirements</b> <br/><br/> Clinical Workflow<br/>Patient Pathway]
IHE[<b>Analysis & Design - Vol 1</b> <br/><br/>IHE + EURDICE]
HL7[<b>Interfaces - Vol 2</b> <br/><br/> HL7 FHIR REST API and V2/FHIR Messages]
Data[<b>Data Models and Domain Archetypes - Vol 3</b> <br/><br/> NHS England, EHDS, HL7, openEHR, etc]
Artefacts[<b>Artefacts, Entities & Data Contracts - Vol 4</b> <br/><br/>Canonical Data Model]
User --> IHE
IHE --> HL7
IHE --> Data
Data --> Artefacts
Artefacts --> |Constrains| HL7
classDef pink fill:#F8CECC;
classDef blue fill:#DAE8FC;
classDef purple fill:#E1D5E7;
class Data,Artefacts blue;
class HL7 pink;
class IHE purple;
| Menu Item | Description | Audience | |
|---|---|---|---|
| Analysis and Design (Volume 1) | Description of the processes and corresponding technical frameworks | General | |
| Interfaces (Volume 2) | Description of the processes and corresponding technical frameworks (HL7 v2 and FHIR Interactions) | Detailed Technical (Integration Developer) | |
| Data Models (Volume 3) | NHS North West Forms, Templates, Reports, and Compositions | Data Modeling (Detailed Technical) | |
| Artefacts (Volume 4) | NHS North West Common Data Models | Detailed Technical | |
| Development | Testing, Suppport and Architecture | Detailed Technical (Developer) |
| Diagnostic Process | Analysis and Design | Interfaces | Domain Archetype |
|---|---|---|---|
| Test Workflow Management | Laboratory Testing Workflow (LTW) | FHIR Workflow LAB-4 and LAB-5 | Work Order Laboratory Analyte Result |
| Laboratory Order | Laboratory Testing Workflow (LTW) | Message Exchange [MQ] LAB-1 | North West Genomics Test Order |
| Health Data API (HIE/EURDICE) | Resource Access [IPA/QEDm] | ||
| Inter Laboratory Workflow (ILW) | Message Exchange [MQ] | ||
| Laboratory Report | Laboratory Testing Workflow (LTW) | Message Exchange [MQ] LAB-3 Document Exchange [MHD] MDM_T02 |
North West Genomics Test Report |
| Health Data API (HIE/EURDICE) | Resource Access [IPA/QEDm] | ||
| Health Data API (HIE/EURDICE) | Document Exchange [MHD] ITI-67 ITI-68 | DocumentReference[MHD]/Document Entry[XDS] plus Future - FHIR Document HL7 Europe Laboratory Report |
|
| Specimen Collection | Future - Specimen Event Tracking (SET) | Resource Access [IPA/QEDm] | |
| API Security | API Security | Authorisation [IUA] OAuth2 |
UK edition of SNOMED (83821000000107)
Package hl7.fhir.uv.extensions.r4#5.2.0 This IG defines the global extensions - the ones defined for everyone. These extensions are always in scope wherever FHIR is being used (built Mon, Feb 10, 2025 21:45+1100+11:00) |
Package hl7.fhir.uv.extensions.r4#5.3.0 This IG defines the global extensions - the ones defined for everyone. These extensions are always in scope wherever FHIR is being used (built Sat, May 16, 2026 18:32+1000+10:00) |
Package hl7.fhir.uv.xver-r5.r4#0.1.0 Extensions for Using Data Elements from FHIR R5 in FHIR R4 (built Fri, Mar 20, 2026 15:40+1100+11:00) |
Package hl7.fhir.eu.extensions.r4#1.3.0 This guide lists the extensions specified for the European REALM. (built Fri, Mar 27, 2026 19:47+0100+01:00) |
Package ihe.pharm.mpd.r4#1.0.0-comment-2 ImplementationGuide for IHE Pharmacy Medication Prescription and Dispense (MPD) profile (built Tue, May 27, 2025 16:32+0200+02:00) |
Package hl7.fhir.eu.base#2.0.0 This guide collects base and core profiles to be used in the European context. It also includes common artifacts, such as the profiles describing the European Health Insurance Card. (built Mon, Apr 27, 2026 22:40+0300+03:00) |
Package fhir.r4.ukcore.stu3.currentbuild#0.0.19-pre-release UK Core FHIR profiles and Assets |
Package hl7.fhir.eu.laboratory#2.0.0 This guide describes how the Laboratory Report can be represented in the European REALM. (built Tue, May 5, 2026 16:28+0200+02:00) |
Package hl7.fhir.uv.sdc#3.0.0 The SDC specification provides an infrastructure to standardize the capture and expanded use of patient-level data collected within an EHR. |
Package ihe.iti.balp#1.1.4 The Basic Audit Log Patterns (BALP) Implementation Guide is a Content Profile that defines some basic and reusable AuditEvent patterns. This includes basic audit log profiles for FHIR RESTful operations to be used when there is not a more specific audit event defined. A focus is enabling Privacy centric AuditEvent logs that hold well formed indication of the Patient when they are the subject of the activity being recorded in the log. Where a more specific audit event can be defined it should be derived off of these basic patterns. (built Fri, Oct 31, 2025 12:53-0500-05:00) |
Package hl7.fhir.uv.tools.r4#1.1.2 This IG defines the extensions that the tools use internally. Some of these extensions are content that are being evaluated for elevation into the main spec, and others are tooling concerns (built Tue, Mar 24, 2026 11:13+1100+11:00) |
| Role(s) | Contributor(s) |
|---|---|
| North West Genomic Medicine Service Alliance | |
| Alder Hey Children's Hospital Trust | |
| Manchester University NHS Foundation Trust | |
| Liverpool Womens NHS Foundation Trust | |
| The Christie NHS Foundation Trust | |
| NHS England | |
| Staff Engineer | Kevin Mayfield, Aire Logic & Mayfield IS |
IG © 2024+ NHS North West Genomics. Package fhir.nwgenomics.nhs.uk#2.0.0 based on FHIR 4.0.1. Generated 2026-05-30
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