NHS North West Genomics
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: Histotrac Test Codes

Active as of 2026-09-04

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{
  "resourceType" : "CodeSystem",
  "id" : "Histotrac",
  "language" : "en",
  "text" : {
    "status" : "generated",
    "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p class=\"res-header-id\"><b>Generated Narrative: CodeSystem Histotrac</b></p><a name=\"Histotrac\"> </a><a name=\"hcHistotrac\"> </a><p><b>Properties</b></p><p><b>This code system defines the following properties for its concepts</b></p><table class=\"grid\"><tr><td><b>Name</b></td><td><b>Code</b></td><td><b>URI</b></td><td><b>Type</b></td><td><b>Description</b></td></tr><tr><td>category</td><td>category</td><td>https://fhir.nhs.uk/CodeSystem/England-GenomicTestDirectory#category</td><td>code</td><td>Which part of the National Genomic Test Directory this code belongs to - reuses the same category values as CodeSystem-GenomicTestCode/CodeSystem-DigitalGenomicTestServices, plus histocompatibility-immunogenetics for codes outside that scheme</td></tr><tr><td>relatedTestCode</td><td>relatedTestCode</td><td>https://fhir.nwgenomics.nhs.uk/CodeSystem/Histotrac#relatedTestCode</td><td>code</td><td>The Test Code (OBR-4 / ServiceRequest.code) this order-detail concept is ordered under - a $DGTS Genomic/Genetic Test (GT) code, or a local NWTestCode code</td></tr></table><p><b>Concepts</b></p><p>This case-sensitive code system <code>https://fhir.nwgenomics.nhs.uk/CodeSystem/Histotrac</code> provides <b>a fragment</b> that includes following codes:</p><table class=\"codes\"><tr><td style=\"white-space:nowrap\"><b>Code</b></td><td><b>Display</b></td><td><b>category</b></td><td><b>relatedTestCode</b></td></tr><tr><td style=\"white-space:nowrap\">C1-Post-PB<a name=\"Histotrac-C1-Post-PB\"> </a></td><td>Chimerism Peripheral Blood (PB)</td><td>chimerism</td><td>GT1368</td></tr><tr><td style=\"white-space:nowrap\">C2-Post-CD3<a name=\"Histotrac-C2-Post-CD3\"> </a></td><td>Chimerism CD3</td><td>chimerism</td><td>GT1368</td></tr><tr><td style=\"white-space:nowrap\">C3-Post-CD15<a name=\"Histotrac-C3-Post-CD15\"> </a></td><td>Chimerism CD15</td><td>chimerism</td><td>GT1368</td></tr><tr><td style=\"white-space:nowrap\">C5-Post-BM<a name=\"Histotrac-C5-Post-BM\"> </a></td><td>Chimerism Bone Marrow (BM)</td><td>chimerism</td><td>GT1368</td></tr><tr><td style=\"white-space:nowrap\">XTRANSPX_HLAAS<a name=\"Histotrac-XTRANSPX_HLAAS\"> </a></td><td>HLA ANTIBODY SCREENING (TRANSPLANT)</td><td>histocompatibility-immunogenetics</td><td>XTRANSPX_HLAAS</td></tr><tr><td style=\"white-space:nowrap\">HLATypingAntibodyScreening<a name=\"Histotrac-HLATypingAntibodyScreening\"> </a></td><td>HLA Typing + Antibody Screening</td><td>histocompatibility-immunogenetics</td><td>XTRANSPX_HLAAS</td></tr><tr><td style=\"white-space:nowrap\">HLAAntibodyScreening<a name=\"Histotrac-HLAAntibodyScreening\"> </a></td><td>HLA Antibody Screening</td><td>histocompatibility-immunogenetics</td><td>XTRANSPX_HLAAS</td></tr><tr><td style=\"white-space:nowrap\">HLATypeRecipient<a name=\"Histotrac-HLATypeRecipient\"> </a></td><td>HLA Type Recipient</td><td>histocompatibility-immunogenetics</td><td>XTRANSPX_HLAAS</td></tr><tr><td style=\"white-space:nowrap\">DSA<a name=\"Histotrac-DSA\"> </a></td><td>DSA</td><td>histocompatibility-immunogenetics</td><td>XTRANSPX_HLAAS</td></tr><tr><td style=\"white-space:nowrap\">HLAAutoXM<a name=\"Histotrac-HLAAutoXM\"> </a></td><td>HLA Auto XM</td><td>histocompatibility-immunogenetics</td><td>XTRANSPX_HLAAS</td></tr></table></div>"
  },
  "url" : "https://fhir.nwgenomics.nhs.uk/CodeSystem/Histotrac",
  "version" : "2.2.5",
  "name" : "Histotrac",
  "title" : "Histotrac Test Codes",
  "status" : "active",
  "experimental" : false,
  "date" : "2026-09-04",
  "publisher" : "NHS North West Genomics",
  "contact" : [
    {
      "telecom" : [
        {
          "system" : "url",
          "value" : "https://www.nwgenomics.nhs.uk/contact-us"
        }
      ]
    }
  ],
  "description" : "Local order-detail codes from **Histotrac**, the Histocompatibility and\nImmunogenetics LIMS - see [Histocompatibility and\nImmunogenetics](https://github.com/nw-gmsa/nw-gmsa-use-cases/blob/main/HistocompatibilityAndImmunogenetics.md), [HLA Tests -\nTransplant Ask At Order Entry](Questionnaire-HLATestsTransplantAskAtOrderEntry.html)\nand [Chimerism Test Additional Ask At Order Entry\nQuestions](Questionnaire-ChimerismTestAdditionalAskAtOrderQuestions.html).\n\nUnlike the Test Code carried in OBR-4/`ServiceRequest.code` (a `$DGTS` Genomic/Genetic\nTest (GT) code, or a local [NWTestCode](CodeSystem-NWTestCode.html) code for test\nfamilies with no national code), these concepts model the **Patient Test(s)**\norder-detail restatement seen in the live Histotrac `ORM^O01`/`OML^O21` orders - the\nvalue Histotrac itself carries alongside the Test Code to say which specific\nlineage/panel or transplant test was ordered. Bound to `ServiceRequest.orderDetail`\nvia [HistotracOrderDetail](ValueSet-HistotracOrderDetail.html) - see\n[GenomicTestCodes](ValueSet-GenomicTestCodes.html) for the separate `ServiceRequest.code`\nbinding these relate to via the `relatedTestCode` property below.\n\nSourced as HL7 v2 CE (coded element)-style `code^text^codingSystem` strings from the\n`HISTOTRACEAP` coding system - see each concept's worked example\n([HLA Tests - Transplant](https://github.com/nw-gmsa/nw-gmsa-use-cases/blob/main/HistocompatibilityAndImmunogenetics.md#hla-tests-transplant-ask-at-order-entry),\n[Chimerism Testing](https://github.com/nw-gmsa/nw-gmsa-use-cases/blob/main/HistocompatibilityAndImmunogenetics.md#chimerism-testing-ask-at-order-entry)).\nThese are distinct from the local `NWGMSA` answer options (e.g. `HLAAntibodyScreening`,\n`ChimerismPeripheralBlood`) used on the Ask At Order Entry Questionnaires' own\norder-entry choice items - those model the order-entry UI selection, these are what\nHistotrac itself calls the resulting order.",
  "jurisdiction" : [
    {
      "coding" : [
        {
          "system" : "urn:iso:std:iso:3166",
          "code" : "GB",
          "display" : "United Kingdom of Great Britain and Northern Ireland"
        }
      ]
    }
  ],
  "caseSensitive" : true,
  "content" : "fragment",
  "property" : [
    {
      "code" : "category",
      "uri" : "https://fhir.nhs.uk/CodeSystem/England-GenomicTestDirectory#category",
      "description" : "Which part of the National Genomic Test Directory this code belongs to - reuses the same category values as CodeSystem-GenomicTestCode/CodeSystem-DigitalGenomicTestServices, plus histocompatibility-immunogenetics for codes outside that scheme",
      "type" : "code"
    },
    {
      "code" : "relatedTestCode",
      "uri" : "https://fhir.nwgenomics.nhs.uk/CodeSystem/Histotrac#relatedTestCode",
      "description" : "The Test Code (OBR-4 / ServiceRequest.code) this order-detail concept is ordered under - a $DGTS Genomic/Genetic Test (GT) code, or a local NWTestCode code",
      "type" : "code"
    }
  ],
  "concept" : [
    {
      "code" : "C1-Post-PB",
      "display" : "Chimerism Peripheral Blood (PB)",
      "property" : [
        {
          "code" : "category",
          "valueCode" : "chimerism"
        },
        {
          "code" : "relatedTestCode",
          "valueCode" : "GT1368"
        }
      ]
    },
    {
      "code" : "C2-Post-CD3",
      "display" : "Chimerism CD3",
      "property" : [
        {
          "code" : "category",
          "valueCode" : "chimerism"
        },
        {
          "code" : "relatedTestCode",
          "valueCode" : "GT1368"
        }
      ]
    },
    {
      "code" : "C3-Post-CD15",
      "display" : "Chimerism CD15",
      "property" : [
        {
          "code" : "category",
          "valueCode" : "chimerism"
        },
        {
          "code" : "relatedTestCode",
          "valueCode" : "GT1368"
        }
      ]
    },
    {
      "code" : "C5-Post-BM",
      "display" : "Chimerism Bone Marrow (BM)",
      "property" : [
        {
          "code" : "category",
          "valueCode" : "chimerism"
        },
        {
          "code" : "relatedTestCode",
          "valueCode" : "GT1368"
        }
      ]
    },
    {
      "code" : "XTRANSPX_HLAAS",
      "display" : "HLA ANTIBODY SCREENING (TRANSPLANT)",
      "property" : [
        {
          "code" : "category",
          "valueCode" : "histocompatibility-immunogenetics"
        },
        {
          "code" : "relatedTestCode",
          "valueCode" : "XTRANSPX_HLAAS"
        }
      ]
    },
    {
      "code" : "HLATypingAntibodyScreening",
      "display" : "HLA Typing + Antibody Screening",
      "property" : [
        {
          "code" : "category",
          "valueCode" : "histocompatibility-immunogenetics"
        },
        {
          "code" : "relatedTestCode",
          "valueCode" : "XTRANSPX_HLAAS"
        }
      ]
    },
    {
      "code" : "HLAAntibodyScreening",
      "display" : "HLA Antibody Screening",
      "property" : [
        {
          "code" : "category",
          "valueCode" : "histocompatibility-immunogenetics"
        },
        {
          "code" : "relatedTestCode",
          "valueCode" : "XTRANSPX_HLAAS"
        }
      ]
    },
    {
      "code" : "HLATypeRecipient",
      "display" : "HLA Type Recipient",
      "property" : [
        {
          "code" : "category",
          "valueCode" : "histocompatibility-immunogenetics"
        },
        {
          "code" : "relatedTestCode",
          "valueCode" : "XTRANSPX_HLAAS"
        }
      ]
    },
    {
      "code" : "DSA",
      "display" : "DSA",
      "property" : [
        {
          "code" : "category",
          "valueCode" : "histocompatibility-immunogenetics"
        },
        {
          "code" : "relatedTestCode",
          "valueCode" : "XTRANSPX_HLAAS"
        }
      ]
    },
    {
      "code" : "HLAAutoXM",
      "display" : "HLA Auto XM",
      "property" : [
        {
          "code" : "category",
          "valueCode" : "histocompatibility-immunogenetics"
        },
        {
          "code" : "relatedTestCode",
          "valueCode" : "XTRANSPX_HLAAS"
        }
      ]
    }
  ]
}