NHS North West Genomics
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: Histotrac Test Codes

Active as of 2026-09-04

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<CodeSystem xmlns="http://hl7.org/fhir">
  <id value="Histotrac"/>
  <language value="en"/>
  <text>
    <status value="generated"/>
    <div xmlns="http://www.w3.org/1999/xhtml"><p class="res-header-id"><b>Generated Narrative: CodeSystem Histotrac</b></p><a name="Histotrac"> </a><a name="hcHistotrac"> </a><p><b>Properties</b></p><p><b>This code system defines the following properties for its concepts</b></p><table class="grid"><tr><td><b>Name</b></td><td><b>Code</b></td><td><b>URI</b></td><td><b>Type</b></td><td><b>Description</b></td></tr><tr><td>category</td><td>category</td><td>https://fhir.nhs.uk/CodeSystem/England-GenomicTestDirectory#category</td><td>code</td><td>Which part of the National Genomic Test Directory this code belongs to - reuses the same category values as CodeSystem-GenomicTestCode/CodeSystem-DigitalGenomicTestServices, plus histocompatibility-immunogenetics for codes outside that scheme</td></tr><tr><td>relatedTestCode</td><td>relatedTestCode</td><td>https://fhir.nwgenomics.nhs.uk/CodeSystem/Histotrac#relatedTestCode</td><td>code</td><td>The Test Code (OBR-4 / ServiceRequest.code) this order-detail concept is ordered under - a $DGTS Genomic/Genetic Test (GT) code, or a local NWTestCode code</td></tr></table><p><b>Concepts</b></p><p>This case-sensitive code system <code>https://fhir.nwgenomics.nhs.uk/CodeSystem/Histotrac</code> provides <b>a fragment</b> that includes following codes:</p><table class="codes"><tr><td style="white-space:nowrap"><b>Code</b></td><td><b>Display</b></td><td><b>category</b></td><td><b>relatedTestCode</b></td></tr><tr><td style="white-space:nowrap">C1-Post-PB<a name="Histotrac-C1-Post-PB"> </a></td><td>Chimerism Peripheral Blood (PB)</td><td>chimerism</td><td>GT1368</td></tr><tr><td style="white-space:nowrap">C2-Post-CD3<a name="Histotrac-C2-Post-CD3"> </a></td><td>Chimerism CD3</td><td>chimerism</td><td>GT1368</td></tr><tr><td style="white-space:nowrap">C3-Post-CD15<a name="Histotrac-C3-Post-CD15"> </a></td><td>Chimerism CD15</td><td>chimerism</td><td>GT1368</td></tr><tr><td style="white-space:nowrap">C5-Post-BM<a name="Histotrac-C5-Post-BM"> </a></td><td>Chimerism Bone Marrow (BM)</td><td>chimerism</td><td>GT1368</td></tr><tr><td style="white-space:nowrap">XTRANSPX_HLAAS<a name="Histotrac-XTRANSPX_HLAAS"> </a></td><td>HLA ANTIBODY SCREENING (TRANSPLANT)</td><td>histocompatibility-immunogenetics</td><td>XTRANSPX_HLAAS</td></tr><tr><td style="white-space:nowrap">HLATypingAntibodyScreening<a name="Histotrac-HLATypingAntibodyScreening"> </a></td><td>HLA Typing + Antibody Screening</td><td>histocompatibility-immunogenetics</td><td>XTRANSPX_HLAAS</td></tr><tr><td style="white-space:nowrap">HLAAntibodyScreening<a name="Histotrac-HLAAntibodyScreening"> </a></td><td>HLA Antibody Screening</td><td>histocompatibility-immunogenetics</td><td>XTRANSPX_HLAAS</td></tr><tr><td style="white-space:nowrap">HLATypeRecipient<a name="Histotrac-HLATypeRecipient"> </a></td><td>HLA Type Recipient</td><td>histocompatibility-immunogenetics</td><td>XTRANSPX_HLAAS</td></tr><tr><td style="white-space:nowrap">DSA<a name="Histotrac-DSA"> </a></td><td>DSA</td><td>histocompatibility-immunogenetics</td><td>XTRANSPX_HLAAS</td></tr><tr><td style="white-space:nowrap">HLAAutoXM<a name="Histotrac-HLAAutoXM"> </a></td><td>HLA Auto XM</td><td>histocompatibility-immunogenetics</td><td>XTRANSPX_HLAAS</td></tr></table></div>
  </text>
  <url value="https://fhir.nwgenomics.nhs.uk/CodeSystem/Histotrac"/>
  <version value="2.2.5"/>
  <name value="Histotrac"/>
  <title value="Histotrac Test Codes"/>
  <status value="active"/>
  <experimental value="false"/>
  <date value="2026-09-04"/>
  <publisher value="NHS North West Genomics"/>
  <contact>
    <telecom>
      <system value="url"/>
      <value value="https://www.nwgenomics.nhs.uk/contact-us"/>
    </telecom>
  </contact>
  <description
               value="Local order-detail codes from **Histotrac**, the Histocompatibility and
Immunogenetics LIMS - see [Histocompatibility and
Immunogenetics](https://github.com/nw-gmsa/nw-gmsa-use-cases/blob/main/HistocompatibilityAndImmunogenetics.md), [HLA Tests -
Transplant Ask At Order Entry](Questionnaire-HLATestsTransplantAskAtOrderEntry.html)
and [Chimerism Test Additional Ask At Order Entry
Questions](Questionnaire-ChimerismTestAdditionalAskAtOrderQuestions.html).

Unlike the Test Code carried in OBR-4/`ServiceRequest.code` (a `$DGTS` Genomic/Genetic
Test (GT) code, or a local [NWTestCode](CodeSystem-NWTestCode.html) code for test
families with no national code), these concepts model the **Patient Test(s)**
order-detail restatement seen in the live Histotrac `ORM^O01`/`OML^O21` orders - the
value Histotrac itself carries alongside the Test Code to say which specific
lineage/panel or transplant test was ordered. Bound to `ServiceRequest.orderDetail`
via [HistotracOrderDetail](ValueSet-HistotracOrderDetail.html) - see
[GenomicTestCodes](ValueSet-GenomicTestCodes.html) for the separate `ServiceRequest.code`
binding these relate to via the `relatedTestCode` property below.

Sourced as HL7 v2 CE (coded element)-style `code^text^codingSystem` strings from the
`HISTOTRACEAP` coding system - see each concept's worked example
([HLA Tests - Transplant](https://github.com/nw-gmsa/nw-gmsa-use-cases/blob/main/HistocompatibilityAndImmunogenetics.md#hla-tests-transplant-ask-at-order-entry),
[Chimerism Testing](https://github.com/nw-gmsa/nw-gmsa-use-cases/blob/main/HistocompatibilityAndImmunogenetics.md#chimerism-testing-ask-at-order-entry)).
These are distinct from the local `NWGMSA` answer options (e.g. `HLAAntibodyScreening`,
`ChimerismPeripheralBlood`) used on the Ask At Order Entry Questionnaires' own
order-entry choice items - those model the order-entry UI selection, these are what
Histotrac itself calls the resulting order."/>
  <jurisdiction>
    <coding>
      <system value="urn:iso:std:iso:3166"/>
      <code value="GB"/>
      <display value="United Kingdom of Great Britain and Northern Ireland"/>
    </coding>
  </jurisdiction>
  <caseSensitive value="true"/>
  <content value="fragment"/>
  <property>
    <code value="category"/>
    <uri
         value="https://fhir.nhs.uk/CodeSystem/England-GenomicTestDirectory#category"/>
    <description
                 value="Which part of the National Genomic Test Directory this code belongs to - reuses the same category values as CodeSystem-GenomicTestCode/CodeSystem-DigitalGenomicTestServices, plus histocompatibility-immunogenetics for codes outside that scheme"/>
    <type value="code"/>
  </property>
  <property>
    <code value="relatedTestCode"/>
    <uri
         value="https://fhir.nwgenomics.nhs.uk/CodeSystem/Histotrac#relatedTestCode"/>
    <description
                 value="The Test Code (OBR-4 / ServiceRequest.code) this order-detail concept is ordered under - a $DGTS Genomic/Genetic Test (GT) code, or a local NWTestCode code"/>
    <type value="code"/>
  </property>
  <concept>
    <code value="C1-Post-PB"/>
    <display value="Chimerism Peripheral Blood (PB)"/>
    <property>
      <code value="category"/>
      <valueCode value="chimerism"/>
    </property>
    <property>
      <code value="relatedTestCode"/>
      <valueCode value="GT1368"/>
    </property>
  </concept>
  <concept>
    <code value="C2-Post-CD3"/>
    <display value="Chimerism CD3"/>
    <property>
      <code value="category"/>
      <valueCode value="chimerism"/>
    </property>
    <property>
      <code value="relatedTestCode"/>
      <valueCode value="GT1368"/>
    </property>
  </concept>
  <concept>
    <code value="C3-Post-CD15"/>
    <display value="Chimerism CD15"/>
    <property>
      <code value="category"/>
      <valueCode value="chimerism"/>
    </property>
    <property>
      <code value="relatedTestCode"/>
      <valueCode value="GT1368"/>
    </property>
  </concept>
  <concept>
    <code value="C5-Post-BM"/>
    <display value="Chimerism Bone Marrow (BM)"/>
    <property>
      <code value="category"/>
      <valueCode value="chimerism"/>
    </property>
    <property>
      <code value="relatedTestCode"/>
      <valueCode value="GT1368"/>
    </property>
  </concept>
  <concept>
    <code value="XTRANSPX_HLAAS"/>
    <display value="HLA ANTIBODY SCREENING (TRANSPLANT)"/>
    <property>
      <code value="category"/>
      <valueCode value="histocompatibility-immunogenetics"/>
    </property>
    <property>
      <code value="relatedTestCode"/>
      <valueCode value="XTRANSPX_HLAAS"/>
    </property>
  </concept>
  <concept>
    <code value="HLATypingAntibodyScreening"/>
    <display value="HLA Typing + Antibody Screening"/>
    <property>
      <code value="category"/>
      <valueCode value="histocompatibility-immunogenetics"/>
    </property>
    <property>
      <code value="relatedTestCode"/>
      <valueCode value="XTRANSPX_HLAAS"/>
    </property>
  </concept>
  <concept>
    <code value="HLAAntibodyScreening"/>
    <display value="HLA Antibody Screening"/>
    <property>
      <code value="category"/>
      <valueCode value="histocompatibility-immunogenetics"/>
    </property>
    <property>
      <code value="relatedTestCode"/>
      <valueCode value="XTRANSPX_HLAAS"/>
    </property>
  </concept>
  <concept>
    <code value="HLATypeRecipient"/>
    <display value="HLA Type Recipient"/>
    <property>
      <code value="category"/>
      <valueCode value="histocompatibility-immunogenetics"/>
    </property>
    <property>
      <code value="relatedTestCode"/>
      <valueCode value="XTRANSPX_HLAAS"/>
    </property>
  </concept>
  <concept>
    <code value="DSA"/>
    <display value="DSA"/>
    <property>
      <code value="category"/>
      <valueCode value="histocompatibility-immunogenetics"/>
    </property>
    <property>
      <code value="relatedTestCode"/>
      <valueCode value="XTRANSPX_HLAAS"/>
    </property>
  </concept>
  <concept>
    <code value="HLAAutoXM"/>
    <display value="HLA Auto XM"/>
    <property>
      <code value="category"/>
      <valueCode value="histocompatibility-immunogenetics"/>
    </property>
    <property>
      <code value="relatedTestCode"/>
      <valueCode value="XTRANSPX_HLAAS"/>
    </property>
  </concept>
</CodeSystem>