NHS North West Genomics
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: Bundle 'Message' - Genomics Order ctDNA O21

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{
  "resourceType" : "Bundle",
  "id" : "GenomicsOrderMessage-ctDNA",
  "meta" : {
    "profile" : [
      🔗 "https://fhir.nwgenomics.nhs.uk/StructureDefinition/BundleMessage"
    ]
  },
  "language" : "en",
  "identifier" : {
    "system" : "urn:ietf:rfc:3986",
    "value" : "urn:uuid:1aa724a8-981e-488e-9e6b-7a73e7c3c07a"
  },
  "type" : "message",
  "timestamp" : "2025-10-14T15:59:16+00:00",
  "entry" : [
    {
      "fullUrl" : "urn:uuid:72d8c754-ebd0-4e3c-b6e1-4d99cadb7f50",
      "resource" : {
        "resourceType" : "MessageHeader",
        "id" : "MessageHeaderO21ctDNA",
        "meta" : {
          "lastUpdated" : "2026-07-13T10:39:26+00:00",
          "profile" : [
            🔗 "https://fhir.nwgenomics.nhs.uk/StructureDefinition/MessageHeader"
          ]
        },
        "language" : "en",
        "text" : {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"MessageHeader_MessageHeaderO21ctDNA\"> </a><p class=\"res-header-id\"><b>Generated Narrative: MessageHeader MessageHeaderO21ctDNA</b></p><a name=\"MessageHeaderO21ctDNA\"> </a><a name=\"hcMessageHeaderO21ctDNA\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Last updated: 2026-07-13 10:39:26+0000</p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-MessageHeader.html\">Document Message (MessageHeader)</a></p></div><p><b>event</b>: <a href=\"http://terminology.hl7.org/7.2.0/CodeSystem-v2-0003.html#v2-0003-O21\">event: O21</a> (OML - Laboratory order)</p><h3>Destinations</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Endpoint</b></td><td><b>Receiver</b></td></tr><tr><td style=\"display: none\">*</td><td><a href=\"https://simplifier.net/resolve?scope=fhir.r4.ukcore.stu3.currentbuild@0.29.0-pre-release&amp;canonical=https://fhir.nwgenomics.nhs.uk/Endpoint/NEYAWSSQS\">https://fhir.nwgenomics.nhs.uk/Endpoint/NEYAWSSQS</a></td><td>NEY GMSA (Identifier: <a href=\"NamingSystem-ods-organization-code-namingsystem.html\" title=\"The identifier system for an Organisation registered with the Organisation Data Service (ODS).\">ODS Organisation Code</a>/699N0)</td></tr></table><p><b>sender</b>: Identifier: <a href=\"NamingSystem-ods-organization-code-namingsystem.html\" title=\"The identifier system for an Organisation registered with the Organisation Data Service (ODS).\">ODS Organisation Code</a>/699X0</p><h3>Sources</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Software</b></td><td><b>Endpoint</b></td></tr><tr><td style=\"display: none\">*</td><td>NW GMSA</td><td><a href=\"https://simplifier.net/resolve?scope=fhir.r4.ukcore.stu3.currentbuild@0.29.0-pre-release&amp;canonical=https://fhir.nwgenomics.nhs.uk/Endpoint/iGene\">https://fhir.nwgenomics.nhs.uk/Endpoint/iGene</a></td></tr></table><p><b>focus</b>: <a href=\"Bundle-FHIRDocumentGeneticReportBundle-ctDNA.html#urn-uuid-6e26d6b3-490e-4348-9d6c-37281567d6ec\">ServiceRequest Non-Small Cell Lung Cancer, Multi-target ctDNA combined Multi-target NGS panel, small variant (EGFR, ALK, BRAF, KRAS, MET exon 14 skipping and copy number variations) and structural variant (ROS1, RET, ALK, NTRK1, NTRK2, NTRK3, MET exon</a></p></div>"
        },
        "eventCoding" : {
          "system" : "http://terminology.hl7.org/CodeSystem/v2-0003",
          "code" : "O21"
        },
        "destination" : [
          {
            "endpoint" : "https://fhir.nwgenomics.nhs.uk/Endpoint/NEYAWSSQS",
            "receiver" : {
              "identifier" : {
                "system" : "https://fhir.nhs.uk/Id/ods-organization-code",
                "value" : "699N0"
              },
              "display" : "NEY GMSA"
            }
          }
        ],
        "sender" : {
          "identifier" : {
            "system" : "https://fhir.nhs.uk/Id/ods-organization-code",
            "value" : "699X0"
          }
        },
        "source" : {
          "software" : "NW GMSA",
          "endpoint" : "https://fhir.nwgenomics.nhs.uk/Endpoint/iGene"
        },
        "focus" : [
          {
            "reference" : "urn:uuid:6e26d6b3-490e-4348-9d6c-37281567d6ec",
            "type" : "ServiceRequest"
          }
        ]
      }
    },
    {
      "fullUrl" : "urn:uuid:2160525b-0168-4f40-8ebf-9b053052a62c",
      "resource" : {
        "resourceType" : "Patient",
        "id" : "Patient-Sheffield",
        "meta" : {
          "profile" : [
            🔗 "https://fhir.nwgenomics.nhs.uk/StructureDefinition/Patient"
          ]
        },
        "language" : "en",
        "text" : {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Patient_Patient-Sheffield\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Patient Patient-Sheffield</b></p><a name=\"Patient-Sheffield\"> </a><a name=\"hcPatient-Sheffield\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-Patient.html\">Patient</a></p></div><p style=\"border: 1px #661aff solid; background-color: #e6e6ff; padding: 10px;\">Theon SHEFFIELD (official) Male, DoB: 1986-09-12 ( Patient internal identifier)</p><hr/><table class=\"grid\"><tr><td style=\"background-color: #f3f5da\" title=\"Record is active\">Active:</td><td colspan=\"3\">true</td></tr><tr><td style=\"background-color: #f3f5da\" title=\"Other Id (see the one above)\">Other Id:</td><td colspan=\"3\">National Health Plan Identifier/9737873858\u00a0(use:\u00a0official,\u00a0)</td></tr><tr><td style=\"background-color: #f3f5da\" title=\"Ways to contact the Patient\">Contact Detail</td><td colspan=\"3\">SPITAL STREET SHEFFIELD S3 9LB (home)</td></tr><tr><td style=\"background-color: #f3f5da\" title=\"Patient Links\">Links:</td><td colspan=\"3\"><ul><li>General Practitioner: Sheffield Medical Centre (Identifier: <a href=\"NamingSystem-ods-organization-code-namingsystem.html\" title=\"The identifier system for an Organisation registered with the Organisation Data Service (ODS).\">ODS Organisation Code</a>/C88622)</li></ul></td></tr></table></div>"
        },
        "identifier" : [
          {
            "use" : "official",
            "type" : {
              "coding" : [
                {
                  "system" : "http://terminology.hl7.org/CodeSystem/v2-0203",
                  "code" : "NH"
                }
              ]
            },
            "system" : "https://fhir.nhs.uk/Id/nhs-number",
            "value" : "9737873858"
          },
          {
            "type" : {
              "coding" : [
                {
                  "system" : "http://terminology.hl7.org/CodeSystem/v2-0203",
                  "code" : "PI"
                }
              ]
            },
            "value" : "336292",
            "assigner" : {
              "identifier" : {
                "system" : "https://fhir.nhs.uk/Id/ods-organization-code",
                "value" : "699X0"
              }
            }
          }
        ],
        "active" : true,
        "name" : [
          {
            "use" : "official",
            "family" : "SHEFFIELD",
            "given" : [
              "Theon"
            ]
          }
        ],
        "gender" : "male",
        "birthDate" : "1986-09-12",
        "address" : [
          {
            "use" : "home",
            "type" : "both",
            "line" : [
              "SPITAL STREET"
            ],
            "city" : "SHEFFIELD",
            "postalCode" : "S3 9LB"
          }
        ],
        "generalPractitioner" : [
          {
            "identifier" : {
              "system" : "https://fhir.nhs.uk/Id/ods-organization-code",
              "value" : "C88622"
            },
            "display" : "Sheffield Medical Centre"
          }
        ]
      }
    },
    {
      "fullUrl" : "urn:uuid:6e26d6b3-490e-4348-9d6c-37281567d6ec",
      "resource" : {
        "resourceType" : "ServiceRequest",
        "id" : "ServiceRequest-ctDNA",
        "meta" : {
          "versionId" : "1.0",
          "profile" : [
            🔗 "https://fhir.nwgenomics.nhs.uk/StructureDefinition/ServiceRequest"
          ]
        },
        "language" : "en",
        "text" : {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ServiceRequest_ServiceRequest-ctDNA\"> </a><p class=\"res-header-id\"><b>Generated Narrative: ServiceRequest ServiceRequest-ctDNA</b></p><a name=\"ServiceRequest-ctDNA\"> </a><a name=\"hcServiceRequest-ctDNA\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">version: 1.0</p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-ServiceRequest.html\">ServiceRequest</a></p></div><p><b>identifier</b>: Filler Identifier/T26-59XG</p><p><b>requisition</b>: Placer Group Number/R26-15AY</p><p><b>status</b>: Active</p><p><b>intent</b>: Order</p><p><b>category</b>: <span title=\"Codes:{http://snomed.info/sct 116148004}\">Molecular genetics procedure</span></p><p><b>code</b>: <span title=\"Codes:{https://fhir.nhs.uk/CodeSystem/England-GenomicTestDirectory M4.14}\">Non-Small Cell Lung Cancer, Multi-target ctDNA combined Multi-target NGS panel, small variant (EGFR, ALK, BRAF, KRAS, MET exon 14 skipping and copy number variations) and structural variant (ROS1, RET, ALK, NTRK1, NTRK2, NTRK3, MET exon</span></p><p><b>subject</b>: <a href=\"Bundle-FHIRDocumentGeneticReportBundle-ctDNA.html#urn-uuid-2160525b-0168-4f40-8ebf-9b053052a62c\">Theon SHEFFIELD</a></p><p><b>requester</b>: Identifier: <a href=\"NamingSystem-ods-organization-code-namingsystem.html\" title=\"The identifier system for an Organisation registered with the Organisation Data Service (ODS).\">ODS Organisation Code</a>/RHQ</p><p><b>performer</b>: Identifier: <a href=\"NamingSystem-ods-organization-code-namingsystem.html\" title=\"The identifier system for an Organisation registered with the Organisation Data Service (ODS).\">ODS Organisation Code</a>/699X0</p><p><b>reasonCode</b>: <span title=\"Codes:{https://fhir.nwgenomics.nhs.uk/CodeSystem/GenomicClinicalIndication M4}\">M4</span></p><p><b>specimen</b>: <a href=\"Bundle-FHIRDocumentGeneticReportBundle-ctDNA.html#urn-uuid-b930b4c4-327a-4728-8bb9-f90061914cc5\">Specimen: identifier = Filler Identifier; status = available; type = Blood specimen</a></p></div>"
        },
        "identifier" : [
          {
            "type" : {
              "coding" : [
                {
                  "system" : "http://terminology.hl7.org/CodeSystem/v2-0203",
                  "code" : "FILL"
                }
              ]
            },
            "system" : "https://fhir.nwgenomics.nhs.uk/iGene/ReportIdentifier",
            "value" : "T26-59XG",
            "assigner" : {
              "identifier" : {
                "system" : "https://fhir.nhs.uk/Id/ods-organization-code",
                "value" : "699X0"
              }
            }
          }
        ],
        "requisition" : {
          "type" : {
            "coding" : [
              {
                "system" : "http://terminology.hl7.org/CodeSystem/v2-0203",
                "code" : "PGN"
              }
            ]
          },
          "system" : "https://fhir.nwgenomics.nhs.uk/iGene/ReferralIdentifier",
          "value" : "R26-15AY",
          "assigner" : {
            "identifier" : {
              "system" : "https://fhir.nhs.uk/Id/ods-organization-code",
              "value" : "699X0"
            }
          }
        },
        "status" : "active",
        "intent" : "order",
        "category" : [
          {
            "coding" : [
              {
                "system" : "http://snomed.info/sct",
                "code" : "116148004",
                "display" : "Molecular genetics procedure"
              }
            ]
          }
        ],
        "code" : {
          "coding" : [
            {
              "system" : "https://fhir.nhs.uk/CodeSystem/England-GenomicTestDirectory",
              "code" : "M4.14"
            }
          ]
        },
        "subject" : {
          "reference" : "urn:uuid:2160525b-0168-4f40-8ebf-9b053052a62c",
          "identifier" : {
            "system" : "https://fhir.nhs.uk/Id/nhs-number",
            "value" : "9737873858"
          },
          "display" : "Theon SHEFFIELD"
        },
        "requester" : {
          "type" : "Organization",
          "identifier" : {
            "system" : "https://fhir.nhs.uk/Id/ods-organization-code",
            "value" : "RHQ"
          }
        },
        "performer" : [
          {
            "type" : "Organization",
            "identifier" : {
              "system" : "https://fhir.nhs.uk/Id/ods-organization-code",
              "value" : "699X0"
            }
          }
        ],
        "reasonCode" : [
          {
            "coding" : [
              {
                "system" : "https://fhir.nwgenomics.nhs.uk/CodeSystem/GenomicClinicalIndication",
                "code" : "M4"
              }
            ]
          }
        ],
        "specimen" : [
          {
            "reference" : "urn:uuid:b930b4c4-327a-4728-8bb9-f90061914cc5"
          }
        ]
      }
    },
    {
      "fullUrl" : "urn:uuid:b930b4c4-327a-4728-8bb9-f90061914cc5",
      "resource" : {
        "resourceType" : "Specimen",
        "id" : "Specimen-ctDNA",
        "meta" : {
          "versionId" : "1.0",
          "profile" : [
            🔗 "https://fhir.nwgenomics.nhs.uk/StructureDefinition/Specimen"
          ]
        },
        "language" : "en",
        "text" : {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Specimen_Specimen-ctDNA\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Specimen Specimen-ctDNA</b></p><a name=\"Specimen-ctDNA\"> </a><a name=\"hcSpecimen-ctDNA\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">version: 1.0</p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-Specimen.html\">Specimen</a></p></div><p><b>identifier</b>: Filler Identifier/S26-1K1Q</p><p><b>status</b>: Available</p><p><b>type</b>: <span title=\"Codes:{http://snomed.info/sct 119297000}\">Blood specimen</span></p><p><b>subject</b>: <a href=\"Bundle-FHIRDocumentGeneticReportBundle-ctDNA.html#urn-uuid-2160525b-0168-4f40-8ebf-9b053052a62c\">Theon SHEFFIELD</a></p><h3>Collections</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Collected[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>2026-06-29</td></tr></table></div>"
        },
        "identifier" : [
          {
            "type" : {
              "coding" : [
                {
                  "system" : "http://terminology.hl7.org/CodeSystem/v2-0203",
                  "code" : "FILL"
                }
              ]
            },
            "system" : "https://fhir.nwgenomics.nhs.uk/iGene/SpecimenIdentifier",
            "value" : "S26-1K1Q",
            "assigner" : {
              "identifier" : {
                "system" : "https://fhir.nhs.uk/Id/ods-organization-code",
                "value" : "699X0"
              }
            }
          }
        ],
        "status" : "available",
        "type" : {
          "coding" : [
            {
              "system" : "http://snomed.info/sct",
              "code" : "119297000",
              "display" : "Blood specimen"
            }
          ]
        },
        "subject" : {
          "reference" : "urn:uuid:2160525b-0168-4f40-8ebf-9b053052a62c",
          "identifier" : {
            "system" : "https://fhir.nhs.uk/Id/nhs-number",
            "value" : "9737873858"
          },
          "display" : "Theon SHEFFIELD"
        },
        "collection" : {
          "collectedDateTime" : "2026-06-29"
        }
      }
    }
  ]
}