NHS North West Genomics
2.2.0 - ci-build
NHS North West Genomics
2.2.0 - ci-build
NHS North West Genomics - Local Development build (v2.2.0) built by the FHIR (HL7® FHIR® Standard) Build Tools. See the Directory of published versions
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<identifier>
<value value="SHIRE:CPP:RTST-260416-0"/>
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<type value="message"/>
<timestamp value="2026-04-16T10:38:39+00:00"/>
<entry>
<fullUrl value="urn:uuid:45a1d9f7-aebc-4e5c-bc88-6a39632bc2af"/>
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<language value="en"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="MessageHeader_null"> </a><p class="res-header-id"><b>Generated Narrative: MessageHeader </b></p><p><b>event</b>: <a href="http://terminology.hl7.org/7.3.0/CodeSystem-v2-0003.html#v2-0003-R01">event: R01</a> (ORU/ACK - Unsolicited transmission of an observation message)</p><h3>Destinations</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Endpoint</b></td><td><b>Receiver</b></td></tr><tr><td style="display: none">*</td><td><a href="https://simplifier.net/resolve?scope=fhir.r4.ukcore.stu3.currentbuild@0.29.0-pre-release&canonical=http://fhir.org/packages/fhir.r4.ukcore.stu3.currentbuild/https//fhir.mft.nhs.uk/Endpoint/HODS">https//fhir.mft.nhs.uk/Endpoint/HODS</a></td><td>Identifier: <a href="NamingSystem-ods-organization-code-namingsystem.html" title="The identifier system for an Organisation registered with the Organisation Data Service (ODS).">ODS Organisation Code</a>/HODS</td></tr></table><p><b>sender</b>: Identifier: <a href="NamingSystem-ods-organization-code-namingsystem.html" title="The identifier system for an Organisation registered with the Organisation Data Service (ODS).">ODS Organisation Code</a>/CPP</p><h3>Sources</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Software</b></td><td><b>Endpoint</b></td></tr><tr><td style="display: none">*</td><td>NW GLH</td><td><a href="https://simplifier.net/resolve?scope=fhir.r4.ukcore.stu3.currentbuild@0.29.0-pre-release&canonical=https://fhir.nwgenomics.nhs.uk/Endpoint/SHIRE">https://fhir.nwgenomics.nhs.uk/Endpoint/SHIRE</a></td></tr></table><p><b>focus</b>: <a href="Bundle-Shire2StructuredR01.html#urn-uuid-2ebb9c8d-eb68-42cc-ab53-c07f55869788">Diagnostic Report for 'Karyotype [Identifier] in Bone marrow Nominal' for '->NED LIVERPOOL Unknown, DoB: 1942-06-18 ( National Health Plan Identifier)'</a></p></div>
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<code value="R01"/>
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<destination>
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<receiver>
<identifier>
<system value="https://fhir.nhs.uk/Id/ods-organization-code"/>
<value value="HODS"/>
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</receiver>
</destination>
<sender>
<identifier>
<system value="https://fhir.nhs.uk/Id/ods-organization-code"/>
<value value="CPP"/>
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<source>
<software value="NW GLH"/>
<endpoint value="https://fhir.nwgenomics.nhs.uk/Endpoint/SHIRE"/>
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<focus>
<reference value="urn:uuid:2ebb9c8d-eb68-42cc-ab53-c07f55869788"/>
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<entry>
<fullUrl value="urn:uuid:52f677f9-6ab0-4a95-8b68-8b12762eedfb"/>
<resource>
<Patient>
<language value="en"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="Patient_null"> </a><p class="res-header-id"><b>Generated Narrative: Patient </b></p><p style="border: 1px #661aff solid; background-color: #e6e6ff; padding: 10px;">NED LIVERPOOL Unknown, DoB: 1942-06-18 ( National Health Plan Identifier)</p><hr/><table class="grid"><tr><td style="background-color: #f3f5da" title="Other Id (see the one above)">Other Id:</td><td colspan="3">Patient internal identifier/00123456789</td></tr></table></div>
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<identifier>
<extension
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<valueCodeableConcept>
<coding>
<system
value="https://fhir.hl7.org.uk/CodeSystem/UKCore-NHSNumberVerificationStatusEngland"/>
<code value="05"/>
<display
value="Trace needs to be resolved - (NHS number or patient detail conflict)"/>
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<type>
<coding>
<system value="http://terminology.hl7.org/CodeSystem/v2-0203"/>
<code value="NH"/>
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</type>
<system value="https://fhir.nhs.uk/Id/nhs-number"/>
<value value="9737383206"/>
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<identifier>
<type>
<coding>
<system value="http://terminology.hl7.org/CodeSystem/v2-0203"/>
<code value="PI"/>
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<value value="00123456789"/>
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<name>
<family value="LIVERPOOL"/>
<given value="NED"/>
</name>
<gender value="unknown"/>
<birthDate value="1942-06-18"/>
</Patient>
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<entry>
<fullUrl value="urn:uuid:7b14e763-b7a6-49de-9686-2fcd0e1da322"/>
<resource>
<Observation>
<language value="en"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_null"> </a><p class="res-header-id"><b>Generated Narrative: Observation </b></p><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span></p><p><b>code</b>: <span title="Codes:{http://loinc.org 62356-1}">Chromosome analysis result in ISCN expression</span></p><p><b>subject</b>: <a href="Bundle-Shire2StructuredR01.html#urn-uuid-52f677f9-6ab0-4a95-8b68-8b12762eedfb">NED LIVERPOOL Unknown, DoB: 1942-06-18 ( National Health Plan Identifier)</a></p><p><b>value</b>: 48~50,XY,+X,-Y,-3,-6,-7,del(7)(q?31q36),+8,+11,add(12)(p11.2),+14,+15,-16,+19,+20,+22-,+1~2mar[cp10]</p><p><b>note</b>: </p><blockquote><div><p>48\R\50,XY,+X,-Y,-3,-6,-7,del(7)(q?31q36),+8,+11,add(12)(p11.2),+14,+15,-16,+19,+20,+22- ,+1\R\2mar[cp10] -Amendment 14/10/20</p>
</div></blockquote></div>
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<status value="final"/>
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value="http://terminology.hl7.org/CodeSystem/observation-category"/>
<code value="laboratory"/>
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<system value="http://loinc.org"/>
<code value="62356-1"/>
<display value="Chromosome analysis result in ISCN expression"/>
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<subject>
<reference value="urn:uuid:52f677f9-6ab0-4a95-8b68-8b12762eedfb"/>
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<valueString
value="48~50,XY,+X,-Y,-3,-6,-7,del(7)(q?31q36),+8,+11,add(12)(p11.2),+14,+15,-16,+19,+20,+22-,+1~2mar[cp10]"/>
<note>
<text
value="48\R\50,XY,+X,-Y,-3,-6,-7,del(7)(q?31q36),+8,+11,add(12)(p11.2),+14,+15,-16,+19,+20,+22- ,+1\R\2mar[cp10] -Amendment 14/10/20"/>
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<entry>
<fullUrl value="urn:uuid:b6fedd0a-7cf6-4308-948e-5c9531ccda0d"/>
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<Observation>
<language value="en"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_null"> </a><p class="res-header-id"><b>Generated Narrative: Observation </b></p><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span></p><p><b>code</b>: <span title="Codes:{http://loinc.org 62367-8}">Chromosome analysis panel by FISH</span></p><p><b>subject</b>: <a href="Bundle-Shire2StructuredR01.html#urn-uuid-52f677f9-6ab0-4a95-8b68-8b12762eedfb">NED LIVERPOOL Unknown, DoB: 1942-06-18 ( National Health Plan Identifier)</a></p><p><b>value</b>: 7q deletion detected.</p><blockquote><p><b>component</b></p><p><b>code</b>: <span title="Codes:">Interphase cells positive</span></p><p><b>value</b>: 93 cells</p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: <span title="Codes:{http://loinc.org 62361-1}">Cells counted [#]</span></p><p><b>value</b>: 100 cells</p></blockquote></div>
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<code value="laboratory"/>
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<coding>
<system value="http://loinc.org"/>
<code value="62367-8"/>
<display value="Chromosome analysis panel by FISH"/>
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<subject>
<reference value="urn:uuid:52f677f9-6ab0-4a95-8b68-8b12762eedfb"/>
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<valueString value="7q deletion detected."/>
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<text value="Interphase cells positive"/>
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<system value="http://loinc.org"/>
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<Observation>
<language value="en"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="Observation_null"> </a><p class="res-header-id"><b>Generated Narrative: Observation </b></p><p><b>status</b>: Final</p><p><b>category</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}">Laboratory</span></p><p><b>code</b>: <span title="Codes:{http://loinc.org 62389-2}">Chromosome analysis master panel</span></p><p><b>subject</b>: <a href="Bundle-Shire2StructuredR01.html#urn-uuid-52f677f9-6ab0-4a95-8b68-8b12762eedfb">NED LIVERPOOL Unknown, DoB: 1942-06-18 ( National Health Plan Identifier)</a></p><p><b>hasMember</b>: </p><ul><li><a href="Bundle-Shire2StructuredR01.html#urn-uuid-7b14e763-b7a6-49de-9686-2fcd0e1da322">Observation Chromosome analysis result in ISCN expression</a></li><li><a href="Bundle-Shire2StructuredR01.html#urn-uuid-b6fedd0a-7cf6-4308-948e-5c9531ccda0d">Observation Chromosome analysis panel by FISH</a></li></ul></div>
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value="http://terminology.hl7.org/CodeSystem/observation-category"/>
<code value="laboratory"/>
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<code>
<coding>
<system value="http://loinc.org"/>
<code value="62389-2"/>
<display value="Chromosome analysis master panel"/>
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<subject>
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<hasMember>
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<hasMember>
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<entry>
<fullUrl value="urn:uuid:2ebb9c8d-eb68-42cc-ab53-c07f55869788"/>
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<DiagnosticReport>
<language value="en"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="DiagnosticReport_null"> </a><p class="res-header-id"><b>Generated Narrative: DiagnosticReport </b></p><h2><span title="Codes:{http://loinc.org 33893-9}">Karyotype [Identifier] in Bone marrow Nominal</span> (<span title="Codes:{http://terminology.hl7.org/CodeSystem/v2-0074 GE}">Genetics</span>) </h2><table class="grid"><tr><td>Subject</td><td>NED LIVERPOOL Unknown, DoB: 1942-06-18 ( National Health Plan Identifier)</td></tr></table><p><b>Report Details</b></p><table class="grid"><tr><td><b>Code</b></td><td><b>Value</b></td><td><b>Flags</b></td></tr><tr><td><a href="Bundle-Shire2StructuredR01.html#urn-uuid-d54744fb-f490-44a1-90a0-1bfbce716fc5"><span title="Codes:{http://loinc.org 62389-2}">Chromosome analysis master panel</span></a></td><td/><td>Final</td></tr></table><p>Complex abnormal hyperdiploid karyotype with gains of chromosomes 8 and
11, and loss of 7q and 12p which are recognised findings in myeloid neoplasms
including AML</p></div>
</text>
<status value="corrected"/>
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<coding>
<system value="http://terminology.hl7.org/CodeSystem/v2-0074"/>
<code value="GE"/>
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<code>
<coding>
<system value="http://loinc.org"/>
<code value="33893-9"/>
<display value="Karyotype [Identifier] in Bone marrow Nominal"/>
</coding>
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<subject>
<reference value="urn:uuid:52f677f9-6ab0-4a95-8b68-8b12762eedfb"/>
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<result>
<reference value="urn:uuid:d54744fb-f490-44a1-90a0-1bfbce716fc5"/>
</result>
<conclusion
value="Complex abnormal hyperdiploid karyotype with gains of chromosomes 8 and
11, and loss of 7q and 12p which are recognised findings in myeloid neoplasms
including AML"/>
</DiagnosticReport>
</resource>
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