NHS North West Genomics
2.2.5 - ci-build
NHS North West Genomics - Local Development build (v2.2.5) built by the FHIR (HL7® FHIR® Standard) Build Tools. See the Directory of published versions
| Draft as of 2026-11-05 |
{
"resourceType" : "Questionnaire",
"id" : "ChimerismTestAdditionalAskAtOrderQuestions",
"meta" : {
"profile" : [
🔗 "https://fhir.nwgenomics.nhs.uk/StructureDefinition/NWQuestionnaire"
]
},
"language" : "en",
"text" : {
"status" : "extensions",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p class=\"res-header-id\"><b>Generated Narrative: Questionnaire ChimerismTestAdditionalAskAtOrderQuestions</b></p><a name=\"ChimerismTestAdditionalAskAtOrderQuestions\"> </a><a name=\"hcChimerismTestAdditionalAskAtOrderQuestions\"> </a><div style=\"display: inline-block; background-color: #fbffeb; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-NWQuestionnaire.html\">Questionnaire</a></p></div><b>Structure</b><table border=\"1\" cellpadding=\"0\" cellspacing=\"0\" class=\"xhtTableBorder1\"><tr class=\"xhtRowBorder2\"><th scope=\"col\" style=\"\" class=\"hierarchy xhtCellBorder1\"><a href=\"https://hl7.org/fhir/R4/formats.html#table\" title=\"The linkID for the item\">LinkID</a></th><th scope=\"col\" style=\"\" class=\"hierarchy xhtCellBorder1\"><a href=\"https://hl7.org/fhir/R4/formats.html#table\" title=\"Text for the item\">Text</a></th><th scope=\"col\" style=\"\" class=\"hierarchy xhtCellBorder1\"><a href=\"https://hl7.org/fhir/R4/formats.html#table\" title=\"Minimum and Maximum # of times the item can appear in the instance\">Cardinality</a></th><th scope=\"col\" style=\"\" class=\"hierarchy xhtCellBorder1\"><a href=\"https://hl7.org/fhir/R4/formats.html#table\" title=\"The type of the item\">Type</a></th><th scope=\"col\" style=\"\" class=\"hierarchy xhtCellBorder1\"><a href=\"https://hl7.org/fhir/R4/formats.html#table\" title=\"Additional information about the item\">Description & Constraints</a><span style=\"float: right\"><a href=\"https://hl7.org/fhir/R4/formats.html#table\" title=\"Legend for this format\"><img src=\"data:image/png;base64,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\" alt=\"doco\" style=\"background-color: inherit\"/></a></span></th></tr><tr class=\"xhtRowBorder1 xhtRowEven\"><td style=\"background-image: url(tbl_bck1.png)\" class=\"hierarchy xhtCellBorder1 xhtCellNoWrap\"><img src=\"tbl_spacer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_q_root.gif\" alt=\"\" style=\"background-color: white; background-color: inherit\" title=\"QuestionnaireRoot\" class=\"hierarchy\"/> </td><td style=\"\" class=\"hierarchy xhtCellBorder1\">**Test Specific Additional Ask At Order Entry Questions** used alongside the\n[common core order form](StructureDefinition-GenomicTestOrder.html) for the\n"Chimerism Testing Blood (PB)" order screen within Histocompatibility and\nImmunogenetics orders (SNOMED CT `909871000000100`) - the same "Test\nSpecific" tier pattern [WGS Test Additional Ask At Order Entry\nQuestions](Questionnaire-WGSTestAdditionalAskAtOrderQuestions.html) follows\nfor WGS orders - see\n[Order Entry Questions](StructureDefinition-GenomicTestOrder.html#order-entry-questions) and\n[Histocompatibility and Immunogenetics](https://github.com/nw-gmsa/nw-gmsa-use-cases/blob/main/HistocompatibilityAndImmunogenetics.md#ask-at-order-entry-questions).\nFor the sibling HLA testing order screen, see\n[HLA Tests - Transplant Ask At Order Entry](Questionnaire-HLATestsTransplantAskAtOrderEntry.html).\n\nExtracted from the `NTE` segments of a live Histotrac `ORM^O01` order for a Chimerism\nTesting (Performable) test - see the worked\n[example](https://github.com/nw-gmsa/nw-gmsa-use-cases/blob/main/HistocompatibilityAndImmunogenetics.md#chimerism-testing-ask-at-order-entry)\nfor the full message. The original order carried two `NTE` segments (Specimen Source,\nthen Patient Test(s)); only Specimen Source is asked here - Specimen Identifier (a\nspeculative future `SPM-2` addition) and Patient Test(s) have both since been dropped\nas Ask At Order Entry questions. See also [Chimerism Testing Result\nPanel](Questionnaire-ChimerismResultPanel.html) for the (separate) structured *result*\npayload this order eventually produces.\n\n**Research summary**: as with [HLA Tests - Transplant](Questionnaire-HLATestsTransplantAskAtOrderEntry.html),\nno NHS England or NHSBT-published order-comms/interoperability standard was found\nspecifically for Chimerism testing order entry. NHSBT's INF136 "User Guide for\nHistocompatibility and Immunogenetics Diagnostics Services" defines `FRM1010` "H&I\nHaematopoietic Stem Cell Transplantation (Recipients & Donors)" as the relevant national\nrequest form for post-transplant chimerism monitoring, but does not publish a\nFHIR/LOINC/SNOMED binding for the specific test-panel or specimen-source values Hive\nuses. See each item below for candidate LOINC/SNOMED codes.</td><td style=\"\" class=\"hierarchy xhtCellBorder1\"/><td style=\"\" class=\"hierarchy xhtCellBorder1\">Questionnaire</td><td style=\"\" class=\"hierarchy xhtCellBorder1\">https://fhir.nwgenomics.nhs.uk/Questionnaire/ChimerismTestAdditionalAskAtOrderQuestions#2.2.5</td></tr>\r\n<tr class=\"xhtRowBorder1 xhtRowOdd\"><td style=\"background-image: url(tbl_bck01.png)\" id=\"item.AskAtOrderEntry\" class=\"hierarchy xhtCellBorder1 xhtCellNoWrap\"><img src=\"tbl_spacer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-group.png\" alt=\"\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"group\" class=\"hierarchy\"/> AskAtOrderEntry</td><td style=\"\" class=\"hierarchy xhtCellBorder1\">Ask At Order Entry Questions</td><td style=\"\" class=\"hierarchy xhtCellBorder1\">0..1</td><td style=\"\" class=\"hierarchy xhtCellBorder1\"><a href=\"https://hl7.org/fhir/R4/codesystem-item-type.html#item-type-group\">group</a></td><td style=\"\" class=\"hierarchy xhtCellBorder1\"/></tr>\r\n<tr class=\"xhtRowBorder1 xhtRowEven\"><td style=\"background-image: url(tbl_bck001.png)\" id=\"item.ChimIG/specimen_source\" class=\"hierarchy xhtCellBorder1 xhtCellNoWrap\"><img src=\"tbl_spacer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-coding.png\" alt=\"\" style=\"background-color: white; background-color: inherit\" title=\"coding\" class=\"hierarchy\"/> <span style=\"position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0\" class=\"sr-only\">AskAtOrderEntry / </span>ChimIG/specimen_source</td><td style=\"\" class=\"hierarchy xhtCellBorder1\">Specimen Source</td><td style=\"\" class=\"hierarchy xhtCellBorder1\">0..1</td><td style=\"\" class=\"hierarchy xhtCellBorder1\"><a href=\"https://hl7.org/fhir/R4/codesystem-item-type.html#item-type-choice\">choice</a></td><td style=\"\" class=\"hierarchy xhtCellBorder1\">Definition: <a href=\"http://hl7.org/fhir/R4/specimen.html#Specimen.type.coding.code\">Specimen.type.coding.code</a><br/>Options: <a href=\"#opt-item.ChimIG/specimen_source\">2 options</a></td></tr>\r\n<tr class=\"xhtRowBorder1 xhtRowOdd\"><td style=\"background-image: url(tbl_bck0010.png)\" id=\"item.ChimIG/specimen_source-designNote\" class=\"hierarchy xhtCellBorder1 xhtCellNoWrap\"><img src=\"tbl_spacer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-display.png\" alt=\"\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"display\" class=\"hierarchy\"/> <span style=\"position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0\" class=\"sr-only\">AskAtOrderEntry / ChimIG/specimen_source / </span>ChimIG/specimen_source-designNote</td><td style=\"\" class=\"hierarchy xhtCellBorder1\">Confirmed as this 2-value list (Blood, Bone marrow) from the Hive/Histotrac\norder-entry UI's Chimerism panel - a different list from the Blood/Buccal/Other\nlist [HLA Tests -\nTransplant](Questionnaire-HLATestsTransplantAskAtOrderEntry.html) uses for the\nsame underlying `code` (LOINC `66746-9`), since the two order screens offer\ndifferent specimen-source options in Hive. Coded against SNOMED CT (the EU/UK/NW-compatible\n[Specimen Type](ValueSet-specimen-type.html) value set's own generic codes -\n`119297000` "Blood specimen" for Blood (PB), `119359002` "Bone marrow specimen"\nfor Bone Marrow (BM)) rather than a local `NWGMSA` code, once converted onto\n`SPM-4` (`Specimen.type`) - see [Chimerism Testing Ask At Order\nEntry](https://github.com/nw-gmsa/nw-gmsa-use-cases/blob/main/HistocompatibilityAndImmunogenetics.md#chimerism-testing-ask-at-order-entry).\nDeliberately given its own `ChimIG/specimen_source` linkId rather than reusing\nthe base [Genomic Test Order](StructureDefinition-GenomicTestOrder.html)'s own\n`LN/66746-9` Specimen Type item - the IG Publisher's Questionnaire derivation\nvalidator does not support a `derivedFrom`/`extends` item reusing a base item's\nlinkId while also declaring more than one `answerOption`. Matches `NTE|1` in the\nlive Histotrac order. Specimen Identifier (a speculative future `SPM-2` addition)\nand Patient Test(s) (`NTE|2`) have since been dropped, leaving Specimen Source as\nthis Questionnaire's only Ask At Order Entry question.</td><td style=\"\" class=\"hierarchy xhtCellBorder1\">0..1</td><td style=\"\" class=\"hierarchy xhtCellBorder1\"><a href=\"https://hl7.org/fhir/R4/codesystem-item-type.html#item-type-display\">display</a></td><td style=\"\" class=\"hierarchy xhtCellBorder1\"/></tr>\r\n<tr class=\"xhtRowBorder1 xhtRowEven\"><td style=\"background-image: url(tbl_bck0000.png)\" id=\"item.ChimIG/specimen_source-reference\" class=\"hierarchy xhtCellBorder1 xhtCellNoWrap\"><img src=\"tbl_spacer.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\"\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon-q-display.png\" alt=\"\" style=\"background-color: white; background-color: inherit\" title=\"display\" class=\"hierarchy\"/> <span style=\"position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0\" class=\"sr-only\">AskAtOrderEntry / ChimIG/specimen_source / </span>ChimIG/specimen_source-reference</td><td style=\"\" class=\"hierarchy xhtCellBorder1\">Post-transplant chimerism monitoring conventionally uses peripheral blood, with\nbone marrow used for deeper/marrow-level engraftment assessment - consistent with\nthis 2-value list. No dedicated NHS-published specimen-type binding specific to\nH&I chimerism testing was found; the generic [Specimen\nType](ValueSet-specimen-type.html) SNOMED CT codes above are used instead.</td><td style=\"\" class=\"hierarchy xhtCellBorder1\">0..1</td><td style=\"\" class=\"hierarchy xhtCellBorder1\"><a href=\"https://hl7.org/fhir/R4/codesystem-item-type.html#item-type-display\">display</a></td><td style=\"\" class=\"hierarchy xhtCellBorder1\"/></tr>\r\n<tr><td colspan=\"5\" class=\"hierarchy\"><br/><a href=\"https://hl7.org/fhir/R4/formats.html#table\" title=\"Legend for this format\"><img src=\"data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAQCAYAAAAf8/9hAAAABmJLR0QA/wD/AP+gvaeTAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3goXBCwdPqAP0wAAAldJREFUOMuNk0tIlFEYhp9z/vE2jHkhxXA0zJCMitrUQlq4lnSltEqCFhFG2MJFhIvIFpkEWaTQqjaWZRkp0g26URZkTpbaaOJkDqk10szoODP//7XIMUe0elcfnPd9zsfLOYplGrpRwZaqTtw3K7PtGem7Q6FoidbGgqHVy/HRb669R+56zx7eRV1L31JGxYbBtjKK93cxeqfyQHbehkZbUkK20goELEuIzEd+dHS+qz/Y8PTSif0FnGkbiwcAjHaU1+QWOptFiyCLp/LnKptpqIuXHx6rbR26kJcBX3yLgBfnd7CxwJmflpP2wUg0HIAoUUpZBmKzELGWcN8nAr6Gpu7tLU/CkwAaoKTWRSQyt89Q8w6J+oVQkKnBoblH7V0PPvUOvDYXfopE/SJmALsxnVm6LbkotrUtNowMeIrVrBcBpaMmdS0j9df7abpSuy7HWehwJdt1lhVwi/J58U5beXGAF6c3UXLycw1wdFklArBn87xdh0ZsZtArghBdAA3+OEDVubG4UEzP6x1FOWneHh2VDAHBAt80IbdXDcesNoCvs3E5AFyNSU5nbrDPZpcUEQQTFZiEVx+51fxMhhyJEAgvlriadIJZZksRuwBYMOPBbO3hePVVqgEJhFeUuFLhIPkRP6BQLIBrmMenujm/3g4zc398awIe90Zb5A1vREALqneMcYgP/xVQWlG+Ncu5vgwwlaUNx+3799rfe96u9K0JSDXcOzOTJg4B6IgmXfsygc7/Bvg9g9E58/cDVmGIBOP/zT8Bz1zqWqpbXIsd0O9hajXfL6u4BaOS6SeWAAAAAElFTkSuQmCC\" alt=\"doco\" style=\"background-color: inherit\"/> Documentation for this format</a></td></tr></table><hr/><p><b>Options Sets</b></p><a name=\"opt-item.ChimIG/specimen_source\"> </a><p><b>Answer options for ChimIG/specimen_source </b></p><ul><li style=\"font-size: 11px\">http://snomed.info/sct#119297000 ("Blood specimen")</li><li style=\"font-size: 11px\">http://snomed.info/sct#119359002 ("Bone marrow specimen")</li></ul></div>"
},
"extension" : [
{
"url" : "http://hl7.org/fhir/StructureDefinition/artifact-versionAlgorithm",
"valueCoding" : {
"system" : "http://hl7.org/fhir/version-algorithm",
"code" : "semver"
}
}
],
"url" : "https://fhir.nwgenomics.nhs.uk/Questionnaire/ChimerismTestAdditionalAskAtOrderQuestions",
"version" : "2.2.5",
"title" : "Chimerism Testing Blood (PB) Ask At Order Entry",
"derivedFrom" : [
🔗 "https://fhir.nwgenomics.nhs.uk/Questionnaire/GenomicTestOrder"
],
"_derivedFrom" : [
{
🔗 "extension" : [
{
"url" : "http://hl7.org/fhir/StructureDefinition/questionnaire-derivationType",
"valueCoding" : {
"system" : "http://hl7.org/fhir/questionnaire-derivationType",
"code" : "extends"
}
}
]
}
],
"status" : "draft",
"date" : "2026-11-05T06:40:21+00:00",
"publisher" : "NHS North West Genomics",
"contact" : [
{
"telecom" : [
{
"system" : "url",
"value" : "https://www.nwgenomics.nhs.uk/contact-us"
}
]
}
],
"description" : "**Test Specific Additional Ask At Order Entry Questions** used alongside the\n[common core order form](StructureDefinition-GenomicTestOrder.html) for the\n\"Chimerism Testing Blood (PB)\" order screen within Histocompatibility and\nImmunogenetics orders (SNOMED CT `909871000000100`) - the same \"Test\nSpecific\" tier pattern [WGS Test Additional Ask At Order Entry\nQuestions](Questionnaire-WGSTestAdditionalAskAtOrderQuestions.html) follows\nfor WGS orders - see\n[Order Entry Questions](StructureDefinition-GenomicTestOrder.html#order-entry-questions) and\n[Histocompatibility and Immunogenetics](https://github.com/nw-gmsa/nw-gmsa-use-cases/blob/main/HistocompatibilityAndImmunogenetics.md#ask-at-order-entry-questions).\nFor the sibling HLA testing order screen, see\n[HLA Tests - Transplant Ask At Order Entry](Questionnaire-HLATestsTransplantAskAtOrderEntry.html).\n\nExtracted from the `NTE` segments of a live Histotrac `ORM^O01` order for a Chimerism\nTesting (Performable) test - see the worked\n[example](https://github.com/nw-gmsa/nw-gmsa-use-cases/blob/main/HistocompatibilityAndImmunogenetics.md#chimerism-testing-ask-at-order-entry)\nfor the full message. The original order carried two `NTE` segments (Specimen Source,\nthen Patient Test(s)); only Specimen Source is asked here - Specimen Identifier (a\nspeculative future `SPM-2` addition) and Patient Test(s) have both since been dropped\nas Ask At Order Entry questions. See also [Chimerism Testing Result\nPanel](Questionnaire-ChimerismResultPanel.html) for the (separate) structured *result*\npayload this order eventually produces.\n\n**Research summary**: as with [HLA Tests - Transplant](Questionnaire-HLATestsTransplantAskAtOrderEntry.html),\nno NHS England or NHSBT-published order-comms/interoperability standard was found\nspecifically for Chimerism testing order entry. NHSBT's INF136 \"User Guide for\nHistocompatibility and Immunogenetics Diagnostics Services\" defines `FRM1010` \"H&I\nHaematopoietic Stem Cell Transplantation (Recipients & Donors)\" as the relevant national\nrequest form for post-transplant chimerism monitoring, but does not publish a\nFHIR/LOINC/SNOMED binding for the specific test-panel or specimen-source values Hive\nuses. See each item below for candidate LOINC/SNOMED codes.",
"jurisdiction" : [
{
"coding" : [
{
"system" : "urn:iso:std:iso:3166",
"code" : "GB",
"display" : "United Kingdom of Great Britain and Northern Ireland"
}
]
}
],
"item" : [
{
"linkId" : "AskAtOrderEntry",
"text" : "Ask At Order Entry Questions",
"type" : "group",
"item" : [
{
"linkId" : "ChimIG/specimen_source",
"definition" : "http://hl7.org/fhir/StructureDefinition/Specimen#Specimen.type.coding.code",
"code" : [
{
"system" : "http://loinc.org",
"code" : "66746-9",
"display" : "Specimen Type"
},
{
"system" : "http://snomed.info/sct",
"code" : "123038009",
"display" : "Specimen"
}
],
"text" : "Specimen Source",
"type" : "choice",
"answerOption" : [
{
"valueCoding" : {
"system" : "http://snomed.info/sct",
"code" : "119297000",
"display" : "Blood specimen"
}
},
{
"valueCoding" : {
"system" : "http://snomed.info/sct",
"code" : "119359002",
"display" : "Bone marrow specimen"
}
}
],
"item" : [
{
"extension" : [
{
"url" : "http://hl7.org/fhir/StructureDefinition/questionnaire-itemControl",
"valueCodeableConcept" : {
"coding" : [
{
"system" : "http://hl7.org/fhir/questionnaire-item-control",
"code" : "help"
}
]
}
}
],
"linkId" : "ChimIG/specimen_source-designNote",
"text" : "Confirmed as this 2-value list (Blood, Bone marrow) from the Hive/Histotrac\norder-entry UI's Chimerism panel - a different list from the Blood/Buccal/Other\nlist [HLA Tests -\nTransplant](Questionnaire-HLATestsTransplantAskAtOrderEntry.html) uses for the\nsame underlying `code` (LOINC `66746-9`), since the two order screens offer\ndifferent specimen-source options in Hive. Coded against SNOMED CT (the EU/UK/NW-compatible\n[Specimen Type](ValueSet-specimen-type.html) value set's own generic codes -\n`119297000` \"Blood specimen\" for Blood (PB), `119359002` \"Bone marrow specimen\"\nfor Bone Marrow (BM)) rather than a local `NWGMSA` code, once converted onto\n`SPM-4` (`Specimen.type`) - see [Chimerism Testing Ask At Order\nEntry](https://github.com/nw-gmsa/nw-gmsa-use-cases/blob/main/HistocompatibilityAndImmunogenetics.md#chimerism-testing-ask-at-order-entry).\nDeliberately given its own `ChimIG/specimen_source` linkId rather than reusing\nthe base [Genomic Test Order](StructureDefinition-GenomicTestOrder.html)'s own\n`LN/66746-9` Specimen Type item - the IG Publisher's Questionnaire derivation\nvalidator does not support a `derivedFrom`/`extends` item reusing a base item's\nlinkId while also declaring more than one `answerOption`. Matches `NTE|1` in the\nlive Histotrac order. Specimen Identifier (a speculative future `SPM-2` addition)\nand Patient Test(s) (`NTE|2`) have since been dropped, leaving Specimen Source as\nthis Questionnaire's only Ask At Order Entry question.",
"type" : "display"
},
{
"extension" : [
{
"url" : "http://hl7.org/fhir/StructureDefinition/questionnaire-itemControl",
"valueCodeableConcept" : {
"coding" : [
{
"system" : "http://hl7.org/fhir/questionnaire-item-control",
"code" : "help"
}
]
}
}
],
"linkId" : "ChimIG/specimen_source-reference",
"text" : "Post-transplant chimerism monitoring conventionally uses peripheral blood, with\nbone marrow used for deeper/marrow-level engraftment assessment - consistent with\nthis 2-value list. No dedicated NHS-published specimen-type binding specific to\nH&I chimerism testing was found; the generic [Specimen\nType](ValueSet-specimen-type.html) SNOMED CT codes above are used instead.",
"type" : "display"
}
]
}
]
}
]
}