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External References

Type Reference Content
web en.wikipedia.org HL7 v3 Clinical Document Architecture
web specifications.openehr.org openEHR
web profiles.ihe.net Recommend IHE-IUA
web browser.ihtsdotools.org Mapping from (not specified) to All Codes SCT ValueSet
web browser.ihtsdotools.org Mapping from All Codes SCT ValueSet to All Codes SCT ValueSet
web www.nwgenomics.nhs.uk contact : https://www.nwgenomics.nhs.uk/contact-us
web hl7.eu Regional Hl7 v2 MDM_T02 The format of the report is PDF, in future for England/EU document sharing the format may change to HL7 EU Laboratory Report
web www.enterpriseintegrationpatterns.com Event Message
web drive.google.com NHS England HL7 v2 ADT Message Specification
web profiles.ihe.net Related to IHE Patient Encounter Management [ITI-31]
web drive.google.com NHS England HL7 v2 ADT Message Specification
web hl7-definition.caristix.com Create Patient HL7 v2.4 ADT_28
web hl7-definition.caristix.com Update Patient HL7 v2.4 ADT_31
web hl7-definition.caristix.com Update (merge) Patient HL7 v2.4 ADT_40
web profiles.ihe.net Related to IHE Patient Identifier Cross-referencing for mobile (PIXm)
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web www.datadictionary.nhs.uk General Medical Council Consultant Code. For more details see: NHS Data Model Dictionary
web www.datadictionary.nhs.uk General Practitioner (GMP) number. For more details see: NHS Data Model Dictionary
web www.datadictionary.nhs.uk NHS Number allocated to the patient in England and Wales. For more details see: NHS Data Model Dictionary
web www.nw-gmsa.nhs.uk
web www.nwgenomics.nhs.uk IG © 2024+ NHS North West Genomics . Package fhir.nwgenomics.nhs.uk#0.1.0 based on FHIR 4.0.1 . Generated 2025-12-19
Links: Table of Contents | QA Report | New Issue | Issues Version History | CC0 | Propose a changeexternal
web github.com Links: Table of Contents | QA Report | New Issue | Issues Version History | CC0 | Propose a changeexternal
web github.com Links: Table of Contents | QA Report | New Issue | Issues Version History | CC0 | Propose a changeexternal
web profiles.ihe.net Links: Table of Contents | QA Report | New Issue | Issues Version History | CC0 | Propose a changeexternal
web www.ihe.net Links: Table of Contents | QA Report | New Issue | Issues Version History | CC0 | Propose a changeexternal
web digital.nhs.uk Manages the Order. This is the function of Genomic Order Management Service and/or GLH LIMS
web www.en13606.org From ISO-13606 The set of information committed to one EHR as a result of a clinical encounter or a record documentation session. Examples of COMPOSITION are Progress note, Laboratory test result form, Radiology report, Referral letter, Clinic visit, Clinic letter, Discharge summary, Functional health assessment, Diabetes review.
web editor.swagger.io The OpenAPISwagger Definition file below, can be viewed using Swagger Editor
web www.england.nhs.uk Genomic Test Directory
web www.england.nhs.uk Test Outcome Code from NHS England Genomics Test Reporting Specification
web confluence.ihtsdotools.org For Implementation Guide see SNOMED CT Implementation Guide for the LOINC Ontology
web en.wikipedia.org Domain Archetype is the result of a collaboration process which aims to form a series of common archetypes within a domain (the domain in this case is Genomics). The initial format for this archetype is often a spreadsheet that is expressed in an electronic format. The format we are using in this guide is HL7 FHIR Questionnaire , other formats can be used such as openEHR Archetype (see Genomic Variant Result )
web ckm.openehr.org Domain Archetype is the result of a collaboration process which aims to form a series of common archetypes within a domain (the domain in this case is Genomics). The initial format for this archetype is often a spreadsheet that is expressed in an electronic format. The format we are using in this guide is HL7 FHIR Questionnaire , other formats can be used such as openEHR Archetype (see Genomic Variant Result )
web en.wikipedia.org The domain archetypes are implemented via a Canonical Data Model , which is common across all technical formats (i.e. HL7 v2 and HL7 FHIR) and is described using HL7 FHIR.
web www.datadictionary.nhs.uk ​ Elements from NHS England FHIR Genomics Implementation Guide have been incorporated into this guide, in particular the use of NHS Data Model and Dictionary Model identifiers and other identifiers already present in HL7 v2 OML and ORU. See Identities and Codes for more details.
web www.enterpriseintegrationpatterns.com Both domain archetypes have a very strong focus on the use of Correlation Identifier (Enterprise Integration Patterns) or Rule 3: Reference Other Aggregates by Identity (Implementing Domain Driven Design) , which is also consistent with IHE/HL7 concepts of Bounded Context (martinfowler.com)
web www.archi-lab.io Both domain archetypes have a very strong focus on the use of Correlation Identifier (Enterprise Integration Patterns) or Rule 3: Reference Other Aggregates by Identity (Implementing Domain Driven Design) , which is also consistent with IHE/HL7 concepts of Bounded Context (martinfowler.com)
web martinfowler.com Both domain archetypes have a very strong focus on the use of Correlation Identifier (Enterprise Integration Patterns) or Rule 3: Reference Other Aggregates by Identity (Implementing Domain Driven Design) , which is also consistent with IHE/HL7 concepts of Bounded Context (martinfowler.com)
web www.datadictionary.nhs.uk This includes making use of FHIR Identifier assigner.identifier.value (HL7 v2 Assigning Facility in a variety of ID types) to distinguish these identifiers between different organisations, the recommendation is to use ODS Code , e.g.
web digital.nhs.uk The coding (B0001, B0300, B0307, etc) is using local laboratory coding, ideally we want all organisations to communicate via standard coding and in the UK this preferred clinical coding is SNOMED CT UK Edition 83821000000107 and the preferred coding standard for units is UCUM . To use local codes would mean 20+ organisation maintaining code mappings between all the different local codesystems, by using SNOMED (or LOINC) this means they only need to maintain mappings between local codes and SNOMED (or LOINC)
web ucum.org The coding (B0001, B0300, B0307, etc) is using local laboratory coding, ideally we want all organisations to communicate via standard coding and in the UK this preferred clinical coding is SNOMED CT UK Edition 83821000000107 and the preferred coding standard for units is UCUM . To use local codes would mean 20+ organisation maintaining code mappings between all the different local codesystems, by using SNOMED (or LOINC) this means they only need to maintain mappings between local codes and SNOMED (or LOINC)
web www.opencodelists.org OpenSAFELY codelists which contain many valuesets used in primary care.
web pathlabs.rlbuht.nhs.uk Internet searches also reveal several NHS Trusts providing documentation around Full Blood Count , this often includes the local coding we saw with the HL7 v2 example. The example below is from University Hospitals of Liverpool Group - Full Blood Count
web en.wikipedia.org Code mappings should be created by a clinical coder . In HL7 FHIR this code mapping is known as a ConceptMap . NHS England has produced instructions for creating a ConceptMap using the NHS England Ontology Server
web digital.nhs.uk Code mappings should be created by a clinical coder . In HL7 FHIR this code mapping is known as a ConceptMap . NHS England has produced instructions for creating a ConceptMap using the NHS England Ontology Server
web digital.nhs.uk Code mappings should be created by a clinical coder . In HL7 FHIR this code mapping is known as a ConceptMap . NHS England has produced instructions for creating a ConceptMap using the NHS England Ontology Server
web snomed.info 147071010000102
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web snomed.info 168331010000106
web snomed.info 558261010000109
web snomed.info 613061010000108
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web snomed.info 613001010000107
web snomed.info 613181010000104
web snomed.info 218801010000106
web snomed.info 528301010000103
web digital.nhs.uk express a preference towards SNOMED CT
web digital.nhs.uk The use of FHIR resources for data which is currently HL7 v2 CE Data Type may need to be questioned. For example mapping of HL7 v2 ORC-16 is to ServiceRequest.requestCode according to ServiceRquest - HL7 v2 Mapping , this is a v2 CE to FHIR CodeableConcept conversion. Curently this is stated as an implied ServiceRequest.requestReference mapping (ISSUE link: NHS England Developer Community Genomics Order Management Service - FHIR ServiceRequest reason )
web developer.community.nhs.uk The use of FHIR resources for data which is currently HL7 v2 CE Data Type may need to be questioned. For example mapping of HL7 v2 ORC-16 is to ServiceRequest.requestCode according to ServiceRquest - HL7 v2 Mapping , this is a v2 CE to FHIR CodeableConcept conversion. Curently this is stated as an implied ServiceRequest.requestReference mapping (ISSUE link: NHS England Developer Community Genomics Order Management Service - FHIR ServiceRequest reason )
web profiles.ihe.net IHE HIE White Paper
web profiles.ihe.net IHE Cross-Enterprise Document Sharing (XDS.b) XML
web profiles.ihe.net IHE Mobile access to Health Documents (MHD) HL7 FHIR
web profiles.ihe.net IHE Query for Existing Data Mobile (QEDm) HL7 FHIR
web fhir.epic.com EPIC on FHIR
web fhir.meditech.com Meditech FHIR
web docs.oracle.com FHIR R4 APIs for Oracle Health Millennium Platform
web profiles.ihe.net The Regional Clinical Data Repository (CDR) will adopt a similar FHIR RESTful approach to that used by Electronic Health Records (EHRs), and will also conform to IHE Query for Existing Data for Mobile (QEDm) and IHE Mobile access to Health Documents (MHD)
web digital.nhs.uk In the future, an alternative messaging approach using FHIR Subscription and Event Notifications is expected to be supported. The outline of this approach is shown below and is related to a similar approach used by NHS England Pathology FHIR specification
web profiles.ihe.net Provide and Register Document Set-b (ITI-41) Provide Document Bundle (ITI-65) Simplified Publish (ITI-105) Generate Metadata (ITI-106)
web profiles.ihe.net Provide and Register Document Set-b (ITI-41) Provide Document Bundle (ITI-65) Simplified Publish (ITI-105) Generate Metadata (ITI-106)
web profiles.ihe.net Provide and Register Document Set-b (ITI-41) Provide Document Bundle (ITI-65) Simplified Publish (ITI-105) Generate Metadata (ITI-106)
web profiles.ihe.net Provide and Register Document Set-b (ITI-41) Provide Document Bundle (ITI-65) Simplified Publish (ITI-105) Generate Metadata (ITI-106)
web profiles.ihe.net Registry Stored Query (ITI-18) Find Document References (ITI-67)
web profiles.ihe.net Registry Stored Query (ITI-18) Find Document References (ITI-67)
web profiles.ihe.net Retrieve Document Set (ITI-43) Retrieve Document (ITI-68)
web profiles.ihe.net Retrieve Document Set (ITI-43) Retrieve Document (ITI-68)
web profiles.ihe.net Mobile Query Existing Data (PCC-44)
web hl7-definition.caristix.com A. HL7 v2.5.1 MFN_M02 - Master files notification - Staff/practitioner master file
web profiles.ihe.net B. IHE Mobile Care Services Discovery (mCSD)
web profiles.ihe.net HL7 v2 MFN_M02 (or IHE ITI-59 )
web hl7-definition.caristix.com The Care Service Update Source sends a HL7 v2.5.1 MFN_M02 - Master files notification - Staff/practitioner master file event to the RIE
web digital.nhs.uk Lookup up existing PractitionerRole via supplied identifiers (MRN or NHS Number) via a FHIR RESTful Search .
web digital.nhs.uk If a PractitionerRole record is found, then update the Patient record via a FHIR RESTful Update
web wiki.ihe.net IHE Inter Laboratory Workflow
web www.ihe.net IHE Laboratory Technical Framework Supplement Inter-Laboratory Workflow (ILW)
web digital.nhs.uk NHS England - Genomic Order Management Service FHIR API a FHIR Workflow based service for managing orders and results at a national level.
web profiles.ihe.net IHE Internet User Authorization (IUA)
web www.ihe.net A. IHE Pathology and Laboratory Medicine (PaLM) Technical Framework - Volume 2a (PaLM TF-2a) Transactions
web www.enterpriseintegrationpatterns.com EIP - Command Message
web martinfowler.com The following messages are used to support creation and updating of the Genomics Test Order aggregation / archetype
web en.wikipedia.org The following messages are used to support creation and updating of the Genomics Test Order aggregation / archetype
web www.enterpriseintegrationpatterns.com Command Message
web www.enterpriseintegrationpatterns.com EIP - Event Message
web www.enterpriseintegrationpatterns.com EIP - Document Message
web www.rcr.ac.uk The Royal College of Radiologists – Reporting networks - understanding the technical options for ORC+OBR/FHIR DiagnosticReport
web www.ihe-europe.net IHE Europe Document Metadata for OBX (value type = ED)/FHIR DocumentReference metadata
web www.digihealthcare.scot Digital Health and Care Scotland - (EH4001) CLINICAL DOCUMENT INDEXING STANDARDS for OBX (value type = ED)/FHIR DocumentReference metadata
web martinfowler.com The following messages are used to support creation and updating of the Genomics Test Report composition
web www.enterpriseintegrationpatterns.com Document Message
web www.enterpriseintegrationpatterns.com In this workflow, both the order and report are shared instead of being sent. The communication between the Order Placer and Filler changes to a conversation rather than messaging pattern around the Fulfillment Task.
web digital.nhs.uk This modernisation is central to the NHS England Genomic Order Management Service FHIR API and the North West Regional Integration will provide the adapter from tradtional workflow to FHIR workflow
web digital.nhs.uk Future expansions will include notifications from the national Genomic Order Management Service FHIR API via its FHIR API.
web www.ihe.net IHE Pathology and Laboratory Medicine (PaLM) Technical Framework - Volume 1 HL7 v2
web digital.nhs.uk Later stages will include the use of Genomic Order Management Service .
web mft.nhs.uk Within the system creating the genomics order, the practitioner will select a form for the test required. Below are several examples from North West Genomic Laboratory Hub - Test Request Forms . How this is implemented will vary between different NHS organisations and systems they use.
web en.wikipedia.org For submission, this form will be converted by the Order Placer to a communication format called HL7 FHIR (and for compatability reasons HL7 v2 . If the Order Placer has a FHIR enabled Electronic Patient Record (e.g. EPIC, Cerner, Meditech, etc), they may use HL7 SDC - Form Data Extraction to assist with this process.
web martinfowler.com This message is an aggregate (DDD) / archetype and so is a collection of FHIR Resources (similar to v2 segements) which is described in Genomic Test Order .
web en.wikipedia.org This message is an aggregate (DDD) / archetype and so is a collection of FHIR Resources (similar to v2 segements) which is described in Genomic Test Order .
web hl7.eu See also HL7 Europe Laboratory Report - ServiceRequest This message can be extended by template (FHIR Questionnaire) which allows the definition of additional questions to be defined for the laboratory order .
web profiles.ihe.net It is not expected the NW GLH Laboratory Information Management System (LIMS) will support UK SNOMED CT, and the RIE will handle the conversion either internally using FHIR ConceptMap or a terminology service with the following capabilities IHE Sharing Valuesets, Codes, and Maps (SVCM)
web www.ihe.net Workflow foundation: The IHE Laboratory and Testing Worflow LTW is used as the reference model for describing laboratory testing processes.
web en.wikipedia.org Canonical model: A standardised model ( Canonical model ), expressed in HL7 FHIR, that can be implemented using HL7 v2, FHIR, and IHE XDS. It aligns with the latest HL7 UK Core and NHS England Data Model and Dictionary. While primarily focused on genomics, it incorporates elements from pathology and radiology for compatibility, and mandates the use of NHS England National Procedure Codes.
web www.nice.org.uk NICE standards
web gettingitrightfirsttime.co.uk Getting It Right First Time (GIRFT) best practice pathways (e.g. Getting It Right First Time (GIRFT) Best Practice Timed Diagnostic Cancer pathways
web www.ihe.net These pathways are technically implmented and generally align with the IHE Laboratory and Testing Worflow LTW (for Imaging workflows see IHE Radiology (RAD) )
web www.ihe.net These pathways are technically implmented and generally align with the IHE Laboratory and Testing Worflow LTW (for Imaging workflows see IHE Radiology (RAD) )
web www.ihe.net Workflow basis: The IHE Laboratory and Testing Worflow LTW serves as the primary reference for describing laboratory testing processes.
web wiki.ihe.net Specimen Event Tracking: See LAB-40 HL7 v2.9 SET IHE Specimen Event Tracking (SET) and Hl7 v2.7 OSM_R26 Unsolicited Specimen Shipment Manifest Message
web hl7-definition.caristix.com Specimen Event Tracking: See LAB-40 HL7 v2.9 SET IHE Specimen Event Tracking (SET) and Hl7 v2.7 OSM_R26 Unsolicited Specimen Shipment Manifest Message
web gettingitrightfirsttime.co.uk The details of this are beyond the scope of this guide, for more details see Getting It Right First Time (GIRFT) Best Practice Timed Diagnostic Cancer pathways
web www.macmillan.org.uk For information on Genomic Tests on the bowel cancer cells , see macmillan.org.uk and NICE DG27 Molecular testing strategies for Lynch syndrome in people with colorectal cancer
web www.nice.org.uk For information on Genomic Tests on the bowel cancer cells , see macmillan.org.uk and NICE DG27 Molecular testing strategies for Lynch syndrome in people with colorectal cancer
web profiles.ihe.net This may include IHE Internet User Authentication [IUA] and IHE Basic Audit Log Patterns[BALP] which includes use of:
web profiles.ihe.net This may include IHE Internet User Authentication [IUA] and IHE Basic Audit Log Patterns[BALP] which includes use of:
web drive.google.com Note: Event trigger definitions based on NHS England HL7 v2 ADT Message Specification which is NHS England's supplement to IHE Technical Framework Volume2: Patient Identity Management [ITI-30] and Patient Encounter Management [ITI-31] .
web profiles.ihe.net Note: Event trigger definitions based on NHS England HL7 v2 ADT Message Specification which is NHS England's supplement to IHE Technical Framework Volume2: Patient Identity Management [ITI-30] and Patient Encounter Management [ITI-31] .
web profiles.ihe.net Note: Event trigger definitions based on NHS England HL7 v2 ADT Message Specification which is NHS England's supplement to IHE Technical Framework Volume2: Patient Identity Management [ITI-30] and Patient Encounter Management [ITI-31] .
web profiles.ihe.net IHE Patient Administration Management (PAM) //HL7 v2 ADT Patient Encounter Management (A02, A08 and A12)
web medcomfhir.dk (Denmark) HL7 FHIR version DK MedCom HospitalNotification
web profiles.ihe.net IHE Mobile access to Health Documents [MHD]
web nhsconnect.github.io INTEROPen/NHS England Care Connect API updated to FHIR R4.
web profiles.ihe.net Retrieve Document [ITI-68]
web profiles.ihe.net Find Document References [ITI-67]
web drive.google.com NHS England HL7 v2 ADT Message Specification
web drive.google.com NHS England IHE PAM and HL7 v2 Messaging Specification from NHS England HL7 v2 ADT Message Specification
web profiles.ihe.net IHE Patient Administration Module (PAM) HL7 v2
web profiles.ihe.net Patient Identifier Cross-referencing for mobile (PIXm)
web profiles.ihe.net Patient Demographics Query for Mobile (PDQm)
web profiles.ihe.net Patient Master Identity Registry (PMIR)
web profiles.ihe.net Patient Identity Feed (ITI-8) Patient Identity Feed FHIR (ITI-104) Mobile Patient Identity Feed (ITI-93)
web profiles.ihe.net Patient Identity Feed (ITI-8) Patient Identity Feed FHIR (ITI-104) Mobile Patient Identity Feed (ITI-93)
web profiles.ihe.net Patient Identity Feed (ITI-8) Patient Identity Feed FHIR (ITI-104) Mobile Patient Identity Feed (ITI-93)
web profiles.ihe.net The Patient Identity Source sends a IHE ITI-8/HL7 v2 A31 (or ITI-104 /FHIR PUT (upsert)) event to the RIE
web digital.nhs.uk Lookup up existing Patient via supplied identifiers (MRN or NHS Number) via a FHIR RESTful Search .
web digital.nhs.uk If a Patient record is found, then update the Patient record via a FHIR RESTful Update
web profiles.ihe.net Mobile Patient Demographics Query (ITI-78) Patient Demographics Query (ITI-21)
web profiles.ihe.net Mobile Patient Demographics Query (ITI-78) Patient Demographics Query (ITI-21)
web profiles.ihe.net IHE Mobile Patient Demographics Query [ITI-78]
web fhir.interweavedigital.com This Encounter represents the overall episode or stay, for further information see Interweave Encounter Grouping
web project-wildfyre.github.io Questionnaire Viewer
web project-wildfyre.github.io Questionnaire Viewer
web project-wildfyre.github.io Master HL7 genetic variant reporting panel Questionnaire Viewer
web project-wildfyre.github.io Questionnaire Viewer
web www.england.nhs.uk NHS Genomic Medicine Service test order forms
web project-wildfyre.github.io Archetype Viewer Questionnaire-GenomicTestOrder
web www.datadictionary.nhs.uk Genomic Laboratory Order Diagnostic Order Patient Administration Patient Identification NHSNumber Identification Medical Record Number Name, date of birth, ethnic category, etc. Case identification / Account Number Hospital Provider Spell Identifier Laboratory Order Order Details Placer Order Number Filler Order Number Placer Group Number Ordering Facility Organisation Code Ordering Practitioner Gene disease assessed Clinical Indication Local Treatment Category Code Genomic Test Code Test Directory Code Specimen Specimen Id Accession Number Shipment Tracking number Supporting Information Genomic (Ask At Order Entry Questions) Consent Pregnant Consanguineous union
web nw-gmsa.github.io Patient
web ckm.openehr.org C. openEHR Genomics Project
web project-wildfyre.github.io Archetype Viewer Questionnaire-GenomicTestReport
web www.datadictionary.nhs.uk Genomic Laboratory Report Diagnostic Report Patient Administration Patient Identification NHSNumber Identification Medical Record Number Name, date of birth, ethnic category, etc. Case identification Hospital Provider Spell Identifier Laboratory Report Order Details Placer Order Number Filler Order Number Ordering Facility Organisation Code Gene disease assessed Clinical Indication Local Treatment Category Code Genomic Test Code Test Directory Code Specimen Accession Number Test Details Report Number Performer Results Interpreter Conclusion (Clinical Indication) Results Genomic Genomic Analysis Narrative Report (PDF) Attachment Finding Variant Implication Diagnostic Implication Therapeutic Implication ProgressRX Genomic Study/Method Gene disease assessed / Clinical Indication Analysis method [Type] NHS England Genomics Test Outcome Genomic Study Analysis Regions Studied / Gene mutations tested
web nw-gmsa.github.io Placer Order Number
web pedigree.readthedocs.io GA4GH Pedigree - Conceptual Model
web mft.nhs.uk NW Genomics - Gen O
web project-wildfyre.github.io Archetype Viewer Questionnaire-Pedigree
web wiki.ihe.net IHE Specimen Event Tracking
web mft.nhs.uk NHS MFT Transport of Samples
web www.datadictionary.nhs.uk NHS Data Model and Dictionary nil, see also RADIOLOGICAL ACCESSION NUMBER Uniquely identifies a Specimen across multiple laboratory systems.
web www.datadictionary.nhs.uk In pathology and genomics, the accession number refers to the Specimen. In imaging the accession number refers to the imaging test RADIOLOGICAL ACCESSION NUMBER
web www.ehealth.fgov.be (copied from BE eHealth Platform Federal Core Profiles ) Extension able to hold a reference and a concept (Temporary solution until https://jira.hl7.org/browse/FHIR-44661 is solved and see Zulip: https://chat.fhir.org/#narrow/stream/179280-fhir.2Finfrastructure-wg/topic/Backporting.20CodeableReference )
web wiki.ihe.net This is a metadata field from XDS/MHD .
web ckm.openehr.org openEHR Project: Genomics
web www.england.nhs.uk NHS England Genomics Test Reporting Specification
web drive.google.com NHS England HL7 v2 DG1 ADT Message Specification
web www.archi-lab.io See Rule 3: Reference Other Aggregates by Identity (Implementing Domain Driven Design) and extends the messasge Enterprise Integration Patterns - Correlation Identifier to a wider set of entities.
web www.enterpriseintegrationpatterns.com See Rule 3: Reference Other Aggregates by Identity (Implementing Domain Driven Design) and extends the messasge Enterprise Integration Patterns - Correlation Identifier to a wider set of entities.
web hl7-definition.caristix.com EI - Entity Identifier
web hl7-definition.caristix.com CX - Extended Composite ID with Check Digit
web www.rcr.ac.uk The Royal College of Radiologists Reporting networks - understanding the technical options
web www.ihe-europe.net Diagnostic Reference: IHE Europe Metadata for exchange medical documents and images
web www.ihe-europe.net IHE Europe Document Metadata (this contains references to NHS England terminology)
web www.digihealthcare.scot Digital Health and Care Scotland - (EH4001) CLINICAL DOCUMENT INDEXING STANDARDS
web profiles.ihe.net Note: links to HL7 FHIR Practitioner has removed several IHE XDS Document Entry fields, and just retained identifier and name. It is expected these values would be available via the NHS England Healthcare Worker API which may conform to IHE Mobile Care Services Discovery (mCSD) interface contracts.
web www.datadictionary.nhs.uk ACTIVITY LOCATION TYPE CODE
web drive.google.com NHS England HL7 v2 PV1 ADT Message Specification
web fhir.interweavedigital.com For detailed notes on FHIR Encounter in a NHS region, see Yorkshire and Humberside Care Record (YHCR) - FHIR Encounter ( YHCR GitHub Repository )
web github.com For detailed notes on FHIR Encounter in a NHS region, see Yorkshire and Humberside Care Record (YHCR) - FHIR Encounter ( YHCR GitHub Repository )
web www.datadictionary.nhs.uk Patient Administration 'NHS Data Model and Dictionary' HOSPITAL PROVIDER SPELL IDENTIFIER
web drive.google.com HL7 v2 Visit Number (PV1-19). See also NHS England HL7 v2 ADT Message Specification PV1 documentation.
web fhir.interweavedigital.com Patient Administration Related to Yorkskhire and Humberside - EncounterGrouping
web www.datadictionary.nhs.uk Patient Administration 'NHS Data Model and Dictionary' LOCAL PATIENT IDENTIFIER
web www.datadictionary.nhs.uk NHS Data Model and Dictionary England/Wales NHS NUMBER , Northern Ireland HEALTH AND CARE NUMBER and Scotland COMMUNITY HEALTH INDEX NUMBER Only traced NHS Number SHOULD be used, un-traced NHS Numbers MUST be clearly indicated.
web www.datadictionary.nhs.uk NHS Data Model and Dictionary England/Wales NHS NUMBER , Northern Ireland HEALTH AND CARE NUMBER and Scotland COMMUNITY HEALTH INDEX NUMBER Only traced NHS Number SHOULD be used, un-traced NHS Numbers MUST be clearly indicated.
web www.datadictionary.nhs.uk NHS Data Model and Dictionary England/Wales NHS NUMBER , Northern Ireland HEALTH AND CARE NUMBER and Scotland COMMUNITY HEALTH INDEX NUMBER Only traced NHS Number SHOULD be used, un-traced NHS Numbers MUST be clearly indicated.
web www.datadictionary.nhs.uk Format: NNNNNNNNNN, values include a checksum, details can be found in NHS NUMBER
web en.wikipedia.org Secondary findings are genetic test results that provide information about variants in a gene unrelated to the primary purpose for the testing, most often discovered when Whole Exome Sequencing (WES) or Whole Genome Sequencing (WGS) is performed. This extension should be used to denote when a genetic finding is being shared as a secondary finding, and ideally refer to a corresponding guideline or policy statement.
web en.wikipedia.org Secondary findings are genetic test results that provide information about variants in a gene unrelated to the primary purpose for the testing, most often discovered when Whole Exome Sequencing (WES) or Whole Genome Sequencing (WGS) is performed. This extension should be used to denote when a genetic finding is being shared as a secondary finding, and ideally refer to a corresponding guideline or policy statement.
web drive.google.com NHS England HL7 v2 OBX ADT Message Specification
web www.datadictionary.nhs.uk Patient Administration 'NHS Data Model and Dictionary' ORGANISATION_CODE
web www.datadictionary.nhs.uk Care Directory 'NHS Data Model and Dictionary' ORGANISATION SITE IDENTIFIER
web drive.google.com NHS England HL7 v2 XON ADT Message Specification
web hl7-definition.caristix.com HL7 v2 XON – Extended Composite Name and Identification Number for Organisations
web profiles.ihe.net IHE Mobile Care Services Discovery (mCSD)
web digital.nhs.uk This reference may be able to point to Care Service Directory services provided by NHS England Organisation Data Terminology - FHIR API (or alternatively downloaded from NHS England Organisation Data Service - CSV Downloads , therefore it is proposed
web digital.nhs.uk This reference may be able to point to Care Service Directory services provided by NHS England Organisation Data Terminology - FHIR API (or alternatively downloaded from NHS England Organisation Data Service - CSV Downloads , therefore it is proposed
web drive.google.com NHS England HL7 v2 PID ADT Message Specification
web drive.google.com NHS England HL7 v2 XCN ADT Message Specification
web hl7-definition.caristix.com HL7 v2 XCN Extended Composite ID Number and Name for Persons
web www.datadictionary.nhs.uk It is not clear in Enterprise/Regional use of FHIR which approach Resource or Reference should be taken, both HL7 v2 and FHIR support Reference aggregate or entities by identity from Dommain Driven Design (DDD) and this appears to also be followed by IHE XDS and DICOM. In addition, NHS England Data Dictionary and NHS England HL7 v2 ADT Message Specification favour Reference NHS England FHIR STU3/R4 specifications around Messaging, tend to favour Resource .
web digital.nhs.uk It is likely that the reference may be able to point to Care Service Directory services provided by NHS England Healthcare Worker - FHIR API in the near future,(or alternatively downloaded from NHS England Organisation Data Service - CSV Downloads . Therefore: it is proposed:
web digital.nhs.uk It is likely that the reference may be able to point to Care Service Directory services provided by NHS England Healthcare Worker - FHIR API in the near future,(or alternatively downloaded from NHS England Organisation Data Service - CSV Downloads . Therefore: it is proposed:
web www.datadictionary.nhs.uk 'Care Directory' 'NHS Data Model and Dictionary' CONSULTANT CODE and GENERAL MEDICAL PRACTITIONER PPD CODE .
web www.datadictionary.nhs.uk 'Care Directory' 'NHS Data Model and Dictionary' CONSULTANT CODE and GENERAL MEDICAL PRACTITIONER PPD CODE .
web fhir.interweavedigital.com Patient Administration Equivalent to Yorkskhire and Humberside - Encounter
web www.ehealth.fgov.be Simple Extension with the type CodeableConcept: (copied from BE eHealth Platform Federal Core Profiles ) Extension able to hold a reference and a concept (Temporary solution until https://jira.hl7.org/browse/FHIR-44661 is solved and see Zulip: https://chat.fhir.org/#narrow/stream/179280-fhir.2Finfrastructure-wg/topic/Backporting.20CodeableReference )
web www.england.nhs.uk See National genomic test directory for cancer on Genomic Test Directory
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web www.england.nhs.uk See National genomic test directory for rare and inherited disease on Genomic Test Directory
web www.england.nhs.uk See NHS England Genomic Test Directory
web www.england.nhs.uk Source: NHS England - North West Region
web profiles.ihe.net IHE Patient Encounter Management [ITI-31]
web www.datadictionary.nhs.uk NHS Data Model and Dictionary ADMISSION METHOD
web www.datadictionary.nhs.uk NHS Data Model and Dictionary ADMISSION SOURCE
web www.datadictionary.nhs.uk NHS Data Model and Dictionary DESTINATION OF DISCHARGE
web www.datadictionary.nhs.uk NHS Data Model and Dictionary DISCHARGE METHOD CODE
web fhir.ch Switzerland DocumentEntry.classCode
web github.com NHS England NRL - Record Category
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web fhir.ch Switzerland DocumentEntry.mimeType
web www.digihealthcare.scot Digital Health and Care Scotland (EH4001) CLINICAL DOCUMENT INDEXING STANDARDS LA Labs
web github.com NHS England NRL -Record Type
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web snomed.info    122575003
web snomed.info    441673008
web en.wikipedia.org In software design, these areas are often referred to as domains . The Genomic Diagnostic Workflow operates across several of these domains — in software architecture terms, this is known as a bounded context .
web martinfowler.com In software design, these areas are often referred to as domains . The Genomic Diagnostic Workflow operates across several of these domains — in software architecture terms, this is known as a bounded context .
web en.wikipedia.org This section of the guide explores the concept of a Domain Archetype — a notion that connects ideas from health informatics, data architecture, and information science with domain-driven design entity models.
web en.wikipedia.org The Domain Archetype concept originates from Data Mesh principles and serves as a bridge between data architecture and software architecture.
web en.wikipedia.org A Domain Archetype may encompass multiple Archetypes and Domain Entities . An Archetype and a Domain Entity can represent the same concept. A Domain Event reflects key interactions in Domain-Driven Design; ideally, each archetype or entity should correspond to a single Domain Event , since handling multiple events can lead to architectural anti-patterns - We should use event-driven message feeds rather than relying on batch data transfers (messages) or the physical exchange of compositions .
web en.wikipedia.org A Domain Archetype may encompass multiple Archetypes and Domain Entities . An Archetype and a Domain Entity can represent the same concept. A Domain Event reflects key interactions in Domain-Driven Design; ideally, each archetype or entity should correspond to a single Domain Event , since handling multiple events can lead to architectural anti-patterns - We should use event-driven message feeds rather than relying on batch data transfers (messages) or the physical exchange of compositions .
web en.wikipedia.org The architecture generally follows Domain Driven Design [DDD] , Domain Driven Design and Data Mesh
web martinfowler.com The architecture generally follows Domain Driven Design [DDD] , Domain Driven Design and Data Mesh
web en.wikipedia.org The architecture generally follows Domain Driven Design [DDD] , Domain Driven Design and Data Mesh
web en.wikipedia.org The Intermediary , North West GMSA Regional Integration Engine (RIE) is an Enterprise Service Bus most commonly known in the NHS as a Trust Integration Engine (TIE).
web www.enterpriseintegrationpatterns.com This implement as series of Enterprise Integration Patterns based around messaging, the diagrams below follow conventions used for these patterns.
web www.enterpriseintegrationpatterns.com The ESB has a Canonical Data Model which is expressed in this Implementation Guide using HL7 FHIR. This model is common to all the exchange formats used in the ESB:
web en.wikipedia.org pipe+hat HL7 v2
web profiles.ihe.net potential use case for sharing reports: XML IHE XDS.b
web nw-gmsa.github.io Digital Health and Care Wales - HL7 ORU_R01 2.5.1 Implementation Guide
web www.rcr.ac.uk Royal College of Radiologist
web www.ihe-europe.net IHE Europe Metadata for exchange medical documents and images see UK content.
web www.datadictionary.nhs.uk NHS Data Model and Dictionary
web www.enterpriseintegrationpatterns.com This canonical model is not specific to Genomics. It is focused on standard message construction patterns in particular CorrelationIdentifier such as Order Numbers and Episode/Stay Identifiers and use of Clinical Coding Systems such as UK SNOMED CT.
web wiki.ihe.net To support genomics workflow, this guide is aligned to enterprise workflow processes described in IHE Laboratory Testing Workflow , terminology from this guide especially around Actors is used throughout this Implementation Guide.
web www.enterpriseintegrationpatterns.com Update Genomic Data Repository ( Wire Tap )
  • First point of entry for HL7 FHIR O21 messages Command Message .
  • Updates internal genomic data repository using FHIR RESTful interactions. ( Messaging Gateway )
web www.enterpriseintegrationpatterns.com First point of entry for HL7 FHIR O21 messages Command Message .
web www.enterpriseintegrationpatterns.com Updates internal genomic data repository using FHIR RESTful interactions. ( Messaging Gateway )
web www.enterpriseintegrationpatterns.com Router ( Message Router )
  • Routes messages based on order metadata.
web www.enterpriseintegrationpatterns.com Transform to HL7 v2 Message ( Message Translator and v2 Canoncial Model )
  • Converts HL7 FHIR O21 messages into HL7 v2.5.1 OML_O21 format.
  • These transformed messages are sent to NW GMSA LIMS iGene.
web www.enterpriseintegrationpatterns.com Transform to HL7 v2 Message ( Message Translator and v2 Canoncial Model )
  • Converts HL7 FHIR O21 messages into HL7 v2.5.1 OML_O21 format.
  • These transformed messages are sent to NW GMSA LIMS iGene.
web www.enterpriseintegrationpatterns.com Genomic Order Management Adaptor Service FHIR API ( Messaging Gateway )
  • Targets NHS England Genomic Order Management Service FHIR API which is the interface to external GMSA.
  • This uses a FHIR RESTful API, similar to the Clinical Data Repository Adaptor, and like this service, the business logic (how to update the repository) is held within Regional Integrations Engine and this is not exposed externally.
web www.enterpriseintegrationpatterns.com NW GMSA LIMS (iGene) ( Document Message )
  • Produces genomic test results in HL7 v2.3 ORU_R01 messages.
  • These are sent into the Enterprise Service Bus (ESB).
web www.enterpriseintegrationpatterns.com Transform to HL7 FHIR Message ( Message Translator and FHIR Canoncial Model )
  • Converts HL7 v2.3 message into a modern HL7 FHIR R01 message.
web www.enterpriseintegrationpatterns.com Transform to HL7 FHIR Message ( Message Translator and FHIR Canoncial Model )
  • Converts HL7 v2.3 message into a modern HL7 FHIR R01 message.
web www.enterpriseintegrationpatterns.com Update Genomic Data Repository & Enrich Content ( Content Enricher )
  • Stores and enhances the message with additional data elements.
  • Provides a consistent, enriched dataset for downstream use.
web www.enterpriseintegrationpatterns.com Reports are sent to the NHS Trust which ordered the test ( Message Router )
web www.enterpriseintegrationpatterns.com Reports are sent to NHS ICS Health Information Exchange (HIE) for sharing the reports within the ICS, this is based on the GP Surgery for the patient which is obtained via a PDS lookup. ( Dynamic Router )
web www.enterpriseintegrationpatterns.com Transform to HL7 v2 Message ( Message Translator and v2 Canoncial Model )
  • Converts enriched content back into a structured HL7 v2.x format for downstream systems that still rely on v2.
  • This ensures backward compatibility with existing hospital systems.
web www.enterpriseintegrationpatterns.com Transform to HL7 v2 Message ( Message Translator and v2 Canoncial Model )
  • Converts enriched content back into a structured HL7 v2.x format for downstream systems that still rely on v2.
  • This ensures backward compatibility with existing hospital systems.
web www.enterpriseintegrationpatterns.com A dedicated Repository Service captures and stores all enriched FHIR data. ( Messaging Gateway )
  • FHIR Repository Adapter converts incoming HL7 FHIR messages into a format suitable for storage.
  • Data is stored in the Clinic Data Repository (IRIS FHIR Repository).
  • Access is available via HL7 FHIR RESTful API.
web digital.nhs.uk NHS England - Application-restricted APIs
web termbrowser.nhs.uk 1022491000000106 and 1491000237105 SNOMED UK Edition
web profiles.ihe.net Is based on IHE Internet User Authorization (IUA) but using client-credentials grant only (at present).
web open.epic.com EPIC HL7 v2 See Outgoing Ancillary Orders (EPR to RIE)
web ehr.meditech.com MEDITECH HL7 v2
web open.epic.com EPIC HL7 v2 See Discrete Genomic Results (RIE to EPIC EPR)
web profiles.ihe.net IHE XDS Cross-Enterprise Document Sharing (XDS.b) or Cross-Enterprise Document Reliable Interchange (XDR) - Provide and Register Document Set-b [ITI-41]
web profiles.ihe.net IHE MHD Mobile access to Health Documents (MHD) - Simplified Publish [ITI-105]
web open.epic.com EPIC Incoming Scanned Document Link Interface Technical Specification
web drive.google.com This is based on the definition of MSH from NHS England HL7 v2 ADT Message Specification .
web drive.google.com This is based on the definition of PID from NHS England HL7 v2 ADT Message Specification and Digital Health and Care Wales - HL7 ORU_R01 2.5.1 Implementation Guide
web drive.google.com This is based on the definition of PV1 from NHS England HL7 v2 ADT Message Specification
web drive.google.com This is based on the definition of PL from NHS England HL7 v2 ADT Message Specification SHOULD be followed and SHALL be used in ORC-12. In addition, this includes of PL.11 to hold organisation ODS code.
web www.rcr.ac.uk This is based on the definitions of NDL from Royal College of Radiologists
web drive.google.com Extended Composite ID Number and Name for Persons. The definition of XCN from NHS England HL7 v2 ADT Message Specification SHOULD be followed and SHALL be used in ORC-12.
web drive.google.com Extended Composite Name and Identification Number for Organizations. The definition of XON from NHS England HL7 v2 ADT Message Specification SHOULD be followed and SHALL be used in ORC-21.
web www.ihe-europe.net IHE Europe Document Metadata (this contains references to NHS England Data Dictionary and Model)
web www.enterpriseintegrationpatterns.com Both guides are effectively merged in this guide and applied to both HL7 v2 and FHIR. The pattern used here is Canonical Data Mode , this can also be applied to other formats such as IHE XDS and DICOM.
web fhir.epic.com For NHS trusts with EPRs with FHIR REST APIs (e.g. EPIC , Oracle and Cerner), the FHIR system used here SHOULD be the same. An OID can be used instead of a FHIR system, this may be defined for use with IHE XDS.
web wiki.ihe.net Genomic diagnostic testing follows the same standardized process defined by the IHE Laboratory Testing Workflow used in traditional laboratory testing. This workflow has been enhanced to support the sharing of laboratory reports (documents) through Integrated Care Systems (ICS). In addition, a new mechanism for sharing laboratory reports has been introduced to establish a regional genomic data repository.
web profiles.ihe.net IHE Mobile Care Services Discovery (mCSD)
web digital.nhs.uk Organisation Data Service (ODS) Organisation Data Terminology - FHIR API
web github.com This implementation guide is built using HL7 igPublisher which has a guide Guidance for FHIR IG Creation It is hosted on GitHub LTW Genomics
web github.com issues can be raised via GitHub Issues
web github.com changes can be raised via GitHub Pull requests
web developer.community.nhs.uk Issues and questions can be raised on NHS England Developer Community
web digital.nhs.uk All test patients (with a NHS Number) are on NHS England Personal Demographics Service - FHIR API (Int environment).
web www.odsdatasearchandexport.nhs.uk P84673
web www.odsdatasearchandexport.nhs.uk N82035
web www.odsdatasearchandexport.nhs.uk P81002
web www.odsdatasearchandexport.nhs.uk B86016
web www.odsdatasearchandexport.nhs.uk F83004
web www.odsdatasearchandexport.nhs.uk M85124
web www.odsdatasearchandexport.nhs.uk W91022
web www.odsdatasearchandexport.nhs.uk C81010
web www.odsdatasearchandexport.nhs.uk Y02790
web www.odsdatasearchandexport.nhs.uk N81027
web www.odsdatasearchandexport.nhs.uk N81087
web www.odsdatasearchandexport.nhs.uk C81065
web www.odsdatasearchandexport.nhs.uk B82045
web www.odsdatasearchandexport.nhs.uk A82025
web www.odsdatasearchandexport.nhs.uk A82038
web www.odsdatasearchandexport.nhs.uk Y02657
web www.odsdatasearchandexport.nhs.uk Y00206
web digital.nhs.uk The APIs are available on the Health and Social Care Network (HSCN)
web 10.165.194.216 See Placer Order Management [LAB-1] and CapabilityStatement
web 10.165.194.217 See Placer Order Management [LAB-1] and CapabilityStatement
web www.oauth.com Integration Testing - OAuth2 client-credentials
web www.enterpriseintegrationpatterns.com Makes use of Messaging Patterns and so in secondary care has considerable middleware via Trust Integration Engines (TIE).
web www.ihe.net LAB-1 and LAB-3 from IHE Laboratory and Testing Workflow (LTW)
web digital.nhs.uk The NHS England Genomic Order Management Service - Process genomic test request is effectively a HL7 Message same as the Genomic Order O21 Command Message. This does not support Genomic Report R01 Document Message
web www.enterpriseintegrationpatterns.com Introduces Event-based Conversation Patterns as an alternative option to Command and Document Messaging Patterns .
web www.enterpriseintegrationpatterns.com Introduces Event-based Conversation Patterns as an alternative option to Command and Document Messaging Patterns .
web profiles.ihe.net IHE Mobile access to Health Documents (MHD) for PDF reports.
web profiles.ihe.net IHE Internet User Access (which includes OAuth2 Authorisation) for access control
web digital.nhs.uk This differs from the current proposal to send in Genomic Test Requests via messaging ( Process genomic test request ), instead they would be shared from the enterprise CDR, and the request to process genomic test request would be Create a new Task
web digital.nhs.uk This differs from the current proposal to send in Genomic Test Requests via messaging ( Process genomic test request ), instead they would be shared from the enterprise CDR, and the request to process genomic test request would be Create a new Task
web www.enterpriseintegrationpatterns.com Uses international standards for Data/Document sharing and FHIR Workflow via Conversation Patterns , this combination removes Command and Document Messaging Patterns
web www.enterpriseintegrationpatterns.com Uses international standards for Data/Document sharing and FHIR Workflow via Conversation Patterns , this combination removes Command and Document Messaging Patterns
web nhsconnect.github.io Yorkshire and Humberside Care Record (FHIR STU3 REST API + Care Connect API )
web www.enterpriseintegrationpatterns.com These exchanges typically use an Aggregator pattern, similar to the approach defined in IHE Cross-Community Access (XCA) , which is implemented in London.
web profiles.ihe.net These exchanges typically use an Aggregator pattern, similar to the approach defined in IHE Cross-Community Access (XCA) , which is implemented in London.
web www.enterpriseintegrationpatterns.com Aggregate Responses

Internal Images

BoundedContext.drawio.png
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Canonical Model.drawio.png
Canonical Model.drawio.png
Clean Architecture.drawio.png
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ConceptMap-Example.png
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Data Mesh Heaxagonal.drawio.png
Data Mesh Heaxagonal.drawio.png
Domain Archetype.drawio.png
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ERIC.drawio.png
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GenomicsIG.drawio.png
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Health Information Exchange.drawio.png
Health Information Exchange.drawio.png
IHEPhaseSend.drawio.png
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IHEPhaseShare.drawio.png
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ILW and FHIR.drawio.png
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Modernisation IHE LTW LAB-3.drawio.png
Modernisation IHE LTW LAB-3.drawio.png
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NLMFormBuilder.png
NW GLH Genomic Testing Request Form – Rare Disease.png
NW GLH Genomic Testing Request Form – Rare Disease.png
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Order Entry.drawio.png
OrderCommunicationAndNotifications.drawio.png
OrderCommunicationAndNotifications.drawio.png
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Questionnaire-Definitions.png
Relationship to NHS England Genomic Order Management Service.drawio.png
Relationship to NHS England Genomic Order Management Service.drawio.png
Relationship to NHS England Pathology.drawio.png
Relationship to NHS England Pathology.drawio.png
Request for Genetic Testing for Haemoglobinopathies.png
Request for Genetic Testing for Haemoglobinopathies.png
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SDC Overview.drawio.png
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